Objective        To explore the functions of left inferior pulmonary vein fat pad (LSPV-FP) on the cardiac electrophysiological characteristics.       Methods       Twelve adult healthy mongrel dogs were anesthetized and ventilated

and their both cervical vagosympathetic trunks were exposed for stimulation. The LSPV-FP was exposed via thoracotomies at the 4th intercostal space of left and right chest. The RR interval

SNRT

WCL

AH interval

HV interval

ERP of atrium were measured in the following status

baseline

vagosympathetic trunks stimulation (VTS)

LSPV-FP ablation. and VTS post LSPV-FP ablation.       Results       No significant electrophysiological change was observed before and after LSPV-FP ablation in the baseline (P0.05). In the status of left vagosympathetic trunks stimulation (LVTS) or right vagosympathetic trunks stimulation (RVTS)

the RR interval

SNRT

WCL

AH interval were lengthened

while the ERP of atrium were shortened.  LSPV-FP ablation significantly attenuated all the changes induced by LVTS (P0.05)

but did not attenuate the changes induced by RVTS(P0.05).       Conclusion        No significant difference in SN and AVN electrophysiology is observed before and after LSPV-FP ablation in baseline. Left vagosympathetic trunk plays a role in cardiac electrophysiology via LSPV-FP.