Objective       To investigate the correlation of serum prostate specific antigen (PSA) with Gleason score and pathological stage after radical prostatectomy in patients with prostate cancer.       Methods       A survey has been performed on 100 inpatients with prostate cancer who underwent robot-assisted laparoscopic radical prostatectomy (rLRP) using the da Vinci robotic surgical system from Jan 2008 to Sep 2010 in the surgery department

urology division of the Prince of Wales Hospital at The Chinese University of Hong Kong. Spearman rank correlation was applied to evaluate the correlation of serum total PSA with Gleason score and pathological stage after radical prostatectomy.       Results       Serum total PSA was significantly positively correlated with Gleason score (r=0.382

P0.01)

but not significantly correlated with pathological stage (r=-0.073

P0.05).       Conclusion       Serum total PSA is correlated with Gleason score but not correlated with pathological stage after radical prostatectomy in patients with prostate cancer.