Objective       To explore the value of whole-brain CT perfusion (CTP) imaging in patients with transient ischemic attack (TIA).       Methods       Whole-brain CTP was performed in 40 patients with clinically diagnosed TIA. The parameter maps of time to peak (TTP)

mean transit time (MTT)

cerebral blood flow (CBF)

and cerebral blood volume (CBV) were analyzed. Dynamic CT angiography (4D-CTA) images were also obtained.       Results       Fifty-eight areas of abnormal perfusion changes corresponding to clinical symptoms were found in 36 of the 40 patients with CTP. Prolonged TTP and MTT

decreased CBF and increased or non-changed CBV were detected in the abnormal perfusion areas. The differences of TTP

MTT and CBF of the affected side compared with those of the contralateral side were significant (P0.05)

but the difference of CBV was not (P0.05). 4D-CTA showed responsible vascular stenosis or occlusion in varying degrees. In the 40 patients

vascular stenosis was found in 32 patients

occlusion in 2 patients and normal in 6 patients.       Conclusion       Overall assessment of TIA can be achieved by whole-brain CTP imaging

which has a great value for the diagnosis and evaluation of TIA.