Objective      To identify the clinical value of prenatal ultrasonography to predict and diagnose twin-to-twin transfusion syndrome.       Methods      The ultrasonographic data of 30 pregnant women of twin-to-twin transfusion syndrome including 60 fetuses who were diagnosed and followed up in our hospital from Aug. 2006 to Mar. 2011 were retrospectively analyzed.       Results      Among the 30 women with 60 fetuses

the S/D value of 17 pregnant women’s fetuses was increased

particularly in the recipient fetus. The 14 cases of recipient fetuses had enlarged heart

but the heart of one donor fetus showed same symptom. There were 8 donors attached to chorionic membrane. Among the 20 cases underwent fetoscopic treatment

15 cases had significantly changes. The fetus having fan-shaped and edge umbilical cord inlet had lower survival rate.       Conclusion      Prenatal ultrasonic examination is helpful to the immediate diagnosis and treatment of twin-to-twin transfusion syndrome

and has a positive effect to improve fetuses’ survival.