Objective       To study the correlative factors for asthma children in Chongqing

China.      Methods       This study enrolled 413 children with asthma from the Pediatric Asthma Outpatient Department and Pediatric Ward of Southwest Hospital of Third Military Medical University from Jun. 2007 to Dec. 2010. The control group included 420 children without asthma from the outpatients and the children who accepted physical examination in our hospital. Questionnaires

examinations

asthma history analysis and following-up were used to determine the correlative factors for asthma children.      Results       Totally 10 factors were investigated and analyzed by Logistic regression analysis. Two factors were excluded and eight factors were included in the end

and among the eight factors there were six risk factors and two protective factors. High risk factors included heredofamilial asthma

atopic constitution

positive response to skin prick test (SPT)

and high total IgE level.      Conclusion       Genetic factors are closely correlated with the development of  asthma children

and atopic constitution is a risk factor for asthma children. Protective factors include breastfeeding and hepatitis A virus (HAV) infection.