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纸质出版:2010
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洪钰锟,迟路湘,宋治远,何国祥,舒茂琴,刘建平,仝识非,景涛,钟理.血管内介入治疗48例多发性大动脉炎疗效观察[J].陆军军医大学学报(原第三军医大学学报),2010,32(23):2541-2544.
Hong Yukun,Chi Luxiang,Song Zhiyuan,He Guoxiang,Shu Maoqin,Liu Jianping,Tong Shifei,Jin Tao,Zhong Li.Curative effect of endovascular therapy on Takayasu arteritis: report of 48 cases[J].J Amry Med Univ (J Third Mil Med Univ),2010,32(23):2541-2544.
洪钰锟,迟路湘,宋治远,何国祥,舒茂琴,刘建平,仝识非,景涛,钟理.血管内介入治疗48例多发性大动脉炎疗效观察[J].陆军军医大学学报(原第三军医大学学报),2010,32(23):2541-2544. DOI:
Hong Yukun,Chi Luxiang,Song Zhiyuan,He Guoxiang,Shu Maoqin,Liu Jianping,Tong Shifei,Jin Tao,Zhong Li.Curative effect of endovascular therapy on Takayasu arteritis: report of 48 cases[J].J Amry Med Univ (J Third Mil Med Univ),2010,32(23):2541-2544. DOI:
目的 观察血管内介入[经皮腔内血管成形术(percutaneous transluminal angioplasty,PTA)和支架置入术(stenting)]治疗多发性大动脉炎(Takayasu arteritis,TA)的疗效。 方法 采用血管内介入(单独PTA或PTA加支架)治疗2002年1月至2009年5月西南医院心血管内科诊断为TA的48例住院患者,其中男性17例,女性31例,年龄19~53(27.6±18.1)岁。分析其治疗结果及平均42.8个月的红细胞沉降率、C反应蛋白、CTA、MRA、多普勒血管超声等随访资料。 结果 通过血管造影在48例TA患者中发现180处病变,并对其中101处严重的病变进行血管内介入治疗。在101处进行血管内介入治疗的病变中,锁骨下动脉/无名动脉29处,颈动脉28处,肾动脉34处,肺动脉2处,冠状动脉8处。101处病变均取得了良好靶病变血运重建术效果,76处(75.2%)没有残余狭窄,25处(24.8%)仅有很少残余狭窄。随访期内(3个月至6年)有3处(12.0%
3/25)仅行PTA治疗的病变发生了再狭窄,有5处(6.5%
5/76)采用PTA+支架治疗的病变发生了再狭窄,所有再狭窄的病变均再次成功行血管内介入治疗,没有出现明显并发症。 结论 单纯PTA或PTA加支架置入术等血管内介入是治疗慢性非活动性TA的一种安全、有效的方法。
Objective To observe the curative effect of endovascular therapy including percutaneous transluminal angioplasty (PTA) and PTA plus stenting on Takayasu arteritis (TA). Methods Forty-eight inpatients with TA (17 males and 31 females) at the age of 19 to 53 years (27.6±18.1 years)
who underwent endovascular therapy(PTA only or PTA plus stenting)in Department of Cardiology
Southwest Hospital
Third Military Medical University (Chongqing
China) from January 2002 to May 2009
were enrolled in this study. Treatment outcome and data including erythrocyte sedimentation rate
C-reactive protein
CTA
MRA
Doppler vascular ultrasound findings obtained during a follow-up period of 42.8 months were analyzed. Results A total of 180 lesions were detected in the 48 patients by angiography. Of the 101 lesions that underwent endovascular therapy
29 were found in subclavian artery and arteria innominata
28 in carotid
34 in renal artery
2 in pulmonary
and 8 in coronary artery
respectively. Good revascularization was achieved in all these lesions. No residual stenosis occurred in 76 lesions (75.2%) with only minimal residual stenosis observed in 25 patients (24.8%). Restenosis was observed in 3 lesions (12.0%
3/25) after treatment with PTA only and in 5 lesions (6.5%
5/76) after treatment with PTA plus stenting during the follow-up period of 3 to 6 months. No significant complication occurred in all recurrent stenoses after endovascular therapy. Conclusion Endovascular therapy including simple PTA or PTA plus stenting is a safe and effective treatment modality for chronic inactive TA.
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