Objective　To study the therapy efficacy of basic and further life support recommended in the 2005 international cardiopulmonary resuscitation guide.　Methods　A total of 386 patients with cardiac arrest admitted to the emergency department of our hospital from September 2007 to September 2009 were randomly divided into control group (group A

n=196) and observation group (group B

n=190). Patients in group A were treated following the 2005 international cardiopulmonary resuscitation guide. Patients in group B were treated following the improved 2005 international cardiopulmonary resuscitation guide. In brief

mentality→respiration→position→open airway→artificial circulation→artificial respiration (artificial circulation/artificial respiration=30/2)were assessed with the traditional ABC adjusted to ACB during basic life support. A cardiopulmonary resuscitation group including 2 physicians and 3 nurses was established to use resuscitation drugs following the improved 2005 international cardiopulmonary resuscitation guide

complete electric defibrilation within 1 min and endotracheal intubation within 3 min

etc. Autonomous circulation and respiration recovery rate and time

24 h survival rate and survival rate after discharge were recorded in patients of two groups.　Results　The autonomous circulation and respiration recovery rates were higher in group A than in group B (15.82% and 26.84% vs 14.80% and 25.26%

P0.05). The autonomous circulation recovery time was 12.38±3.96 min and 7.52±2.87 min respectively in groups A and B. The autonomous respiration recovery time was longer in group A than in group B group (152.70±10.80 min vs 76.56±8.29 min). The 24h survival rate and the survival rate after discharge were higher in group B than in group A（15.82% vs 26.84%

13.27% vs 21.58%

P0.05）.　Conclusion　The improved 2005 international cardiopulmonary resuscitation guide can significantly increase the autonomous circulation and respiration recovery rate

the 24 h survival rate and the survival rate after discharge

and shorten the autonomous circulation and respiration recovery time during cardiopulmonary resuscitation compared with the 2005 international cardiopulmonary resuscitation guide.