Objective  To explore the role of urination guide according to safe bladder capacity in prevention of upper urinary damage in patients with ileal neobladder.    Methods  A total of 91 patients with carcinoma of urinary bladder and receiving reconstruction of bladder with ileum after radical resection from June 2004 to February 2009 in our institute were enrolled in this study. There were 62 patients with regular urodynamic test and urination guide (Group A) and 29 patients without regular urodynamic test and urination guide (Group B). Then parameters from urodynamics

excretory cystography

color ultrasonography and renal function test in group A and group B were compared and analyzed.    Results  Significant difference was found in residual urine volume (RUV) (P0.05)

but not in safe bladder capacity and maximum bladder capacity (P0.05) between 2 groups. Rate of upper urinary damage in group A was significantly lower than that from group B in vesicoureteral reflux

upper urinary tract hydroureterosis

renal dysfunction (P0.05).    Conclusion  Urination guide according to safe bladder capacity contributes to lower rate of upper urinary damage in patients with ileal neobladder.