Li Wei,Lin Ping,Wang Qi.Effect of extensive small cell lung cancer metastasis on patient’s survival[J].J Amry Med Univ (J Third Mil Med Univ),2010,32(17):1861-1864.
Li Wei,Lin Ping,Wang Qi.Effect of extensive small cell lung cancer metastasis on patient’s survival[J].J Amry Med Univ (J Third Mil Med Univ),2010,32(17):1861-1864.DOI:
Objective To retrospectively analyze the effect of extensive small cell lung cancer (SCLC) metastasis on survival of SCLC patients. Methods Kaplan-Meier method and Cox regression were used to analyze the relation between general condition
local invasion
distal metastasis
multiple organ metastasis
metastatic foci and survival of 134 patients with extensive SCLC metastasis
admitted to hospital from January 2003 to December 2008. Results Univariate analysis and multivariate analysis showed that the distal organ metastasis was closely related with the survival of patients with extensive SCLC metastasis (P<0.05). The survival time of SCLC patients with liver and kidney metastasis was the shortest with a median survival time (MST) of only 5 month (RR=0.423)
while the MST of those with lung metastasis was 8 months (RR=-0.450
P0.05). The survival of SCLC patients was not related with their sex
age and general condition
local invasion (including pleural effusion and pericardial effusion)
superior vena cava compression syndrome
multiple organ metastasis
and metastatic foci. Conclusion The survival of SCLC patients is related with distal metastatic organs but not with the general condition