Objective   To assess the therapeutic effect of mini-invasive percutaneous pedicle screw fixation in thoracolumbar fracture using multi-level Sextant system.    Methods   From June 2008 to March 2009

42 thoracolumbar fracture patients in our department were selected. They were divided into 2 groups: 16 cases (11 males and 5 females

age 40.2±8.6) were included in the multi-level Sextant percutaneous pedicle screw fixation group and 26 cases（17 males and 9 females

age 42.4±9.3）were in the open pedicle screw fixation group. The incision size

surgical time

surgical blood loss

correction rate of kyphosis of the 2 groups were compared.    Results   Compared with the open pedicle screw fixation group

patients in the multi-level Sextant percutaneous pedicle screw fixation group experienced a significantly smaller incision size（16.5±1.8 cm vs 10.1±1.0 cm

P0.05）

a significant decrease in surgical blood loss (346.2±138.7 ml vs 81.3±21.9 ml

P0.01) and surgical draining loss (138.6±46.5 ml vs 13.7±4.3 ml

P0.01). Surgical time shortened significantly (2.5±0.7 h vs 1.2±0.6 h

P0.05). There were significant postoperative improvement in Cobb’s angle [(15.4±5.1)°  vs (3.8±2.8)°

P0.01]

sagittal index [(19.7±10.3)°  vs（7.3±9.1）°

P0.01] and anterior height [(63.2±14.6) % vs (86.4±6.9) %

P0.01] of fracture vertebral body in the multi-level Sextant percutaneous pedicle screw fixation group.    Conclusion   With a good command of the surgical indications

mini-invasive percutaneous pedicle screw fixation using multi-level Sextant system is a good therapeutic choice for patients with thoracolumbar fracture.