Objective   To explore the efficacy of allogeneic fibula ring (AFR) grafting combined with posterior internal fixation of pedicle screw to treat lumbar vertebrae tuberculosis.    Methods   Totally 22 patients with single lumbar vertebrae tuberculosis who were admitted in our department from January 2005 to January 2008 and need local and intervertebral fusion with bone graft were retrospectively analyzed. All patients received a total debridement of tuberculosis lesion

AFR grafting

and posterior compressive internal fixation of pedicle screw. A standardized chemotherapy scheme of 3SHRZ/15HRZ was carried out before and after the operation. Waist/back orthosis brace was worn for 3 to 6 months. The outcome of the operation was evaluated through CR

CT and MRI examination in the follow-up at 3

6

12 and 24 months after operation.    Results   In the 18 to 52 months’ follow-up (mean 34.8 months)

all patients had no lumbar vertebra tuberculosis relapsed

no narrowing of intervertebral space

and a fusion rate of 100% in 6 months after operation.     Conclusion   AFR as a supporting graft can restore the intervertebral space and prevent the narrowing. Combined with posterior compressive internal fixation of pedicle screw

the grafting provides a sound architecture for bone fusion

improve the fusion rate and cure rate

and has a satisfying outcome. For single space lumber vertebrae tuberculosis

standard medication before and after operation

enhancing nutrition

local debriment

AFR grafting

and posterior compressive internal fixation of pedicle screw should be recommended.