Objective   To observe the efficiency of clopidogrel combined with emergency corona interventional therapy for non-ST segment elevation myocardial infarction.    Methods   A total of 112 patients with non-ST segment elevation myocardial infarction who were admitted in our hospital from February 2004 to November 2007 were divided into 2 groups at random with 56 patients in each

the experimental group and the control group. All patients were treated with emergency corona interventional therapy and the other routine standard therapies. The experimental group was treated with clopidogrel (75 mg

once per day for 8 weeks)

and the control group administered ticlopidine (250 mg

twice per day for 8 weeks).The two group were followed up for a time of half a year.    Results   The TIMI (thrombolysis in myocardial infarction) myocardial-perfusion grade 3 angiographic flow was achieved in 91.1% of the experimental group

higher than that of the control group (87.5%)

but there was no significant difference between them. What’s more

there was no obvious difference between the 2 group in cardiac functional grading and life-threatening bleeding. The experimental group had significantly lesser hyporrhea

and lower platelet degradation and total white blood cells counts in comparison to the control group. After the followed-up of half a year

there was significant difference between them in combination-end point.     Conclusion   Addition of clopidogrel is effective in emergency corona interventional therapy for non-ST segment elevation myocardial infarction

which can degrade the risk of emergency corona interventional therapy.