Objective   To explore the changes of plasma lipids and uric acid in the military drivers who running on Sichuan-Tibet routs.    Methods   A database of 2 355 military drivers who underwent a special physical check-up by using the standard technique to examine the plasma lipids

uric acid was collected. In this database

the relationships of plasma levels of triglycerides (TG)

high density lipoprotein cholesterol (HDL-C)

uric acid (UA) in those under 25 year-old and those over 26 subjects were evaluated. Parallel analyses were conducted in the parameters of the database.    Results   We found there were 523 (22.21% of all) subjects having significantly higher UA. Among them

216 cases were in under-25 group (12.70%) and 307 cases in over-26 group (46.94%). Totally 423 cases were found hypercholesterimia (34 cases were in under-25 group and 389 cases in over-26 group). Low TC were found in 490 cases (473 were in under-25 group and 17 cases in over-26 group). An increased higher level UA was significantly correlated with hyperlipids.    Conclusion   There are much more subjects with higher level UA in over-26 group than in the under-25 group. In particular

low total cholesterol was more in the under-25 group. Hypertriglyceridemia

low HDL-cholesterol and hyperuricemia seem to be related to the leaders in comparision with the soldiers

whereas hypertension seems to be related mostly to the group at the age of over 26.