YANG Guang-lun,TU Gang,YAO Zhen-xiang,YUE Jun-yi.Expression and clinical significance of EphB4 in breast infiltrating ductal carcinoma: report of 65 cases[J].J Amry Med Univ (J Third Mil Med Univ),2009,31(05):438-440.
YANG Guang-lun,TU Gang,YAO Zhen-xiang,YUE Jun-yi.Expression and clinical significance of EphB4 in breast infiltrating ductal carcinoma: report of 65 cases[J].J Amry Med Univ (J Third Mil Med Univ),2009,31(05):438-440.DOI:
Objective To study the expression and clinical significance of EphB4 in breast infiltrating ductal carcinoma. Methods SP immunohistochemical technique was used to examine the expression of EphB4 in 65 cases of breast infiltrating ductal cancer and 12 matched adjacent tissue samples. Results The level of EphB4 in breast infiltrating ductal cancer was significantly higher than that of adjacent normal tissues (P0.01). EphB4 expression had a positive correlation with histological grade and CerBb-2 (P0.05)
but not with ER
PR and metastasis (P0.05). Conclusion EphB4 plays a crucial role in the occurrence and development of breast cancer.