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纸质出版:2009
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涂运输,阴正勤,李灿,李家文.白内障摘除人工晶体植入联合房角分离治疗原发性闭角型青光眼的临床分析[J].陆军军医大学学报(原第三军医大学学报),2009,31(04):349-351.
TU Yun-shu,YIN Zheng-qin,LI Can,LI Jia-wen.Phacoemulsification and viscogoniosynechialysis for primary angle closure glaucoma[J].J Amry Med Univ (J Third Mil Med Univ),2009,31(04):349-351.
目的 观察超声乳化白内障吸除、加后房型折叠人工晶状体植入联合房角分离术,治疗闭角型青光眼的疗效以及手术适应证的探讨。 方法 已确诊为闭角型青光眼患者46例(46眼),均合并不同程度晶状体混浊。所有病例行超声乳化白内障吸除及后房型折叠人工晶状体植入联合房角分离术,术后随访9~24个月。观察术前术后眼压、视力、前房深度、房角、房水流畅系数(C)与压畅比(PO/C)和降眼压用药数量等的变化。 结果 术后随访最终平均眼压明显低于术前平均眼压 (配对t检验,P0.01),术后最佳矫正视力好于术前(配对秩和检验,P0.01)。前房深度加深(配对t检验,P0.01)。房角全部开放36眼(78.26%)。术后房水流畅系数(C)与压畅比(PO/C)有明显改善(配对t检验,P0.01)。术后平均使用降眼压药数量明显减少 (配对t检验,P0.01)。另有7眼 (15.21%)术后眼压仍25 mmHg,遂行滤过性手术治疗。 结论 晶状体摘除、后房型折叠人工晶状体植入联合房角分离术是治疗原发性闭角型青光眼合的一种有效的选择,但对房角关闭粘连超过270°以上,则有必要联合小梁切除术。
Objective To investigate the clinical effects and indications of phacoemulsification and soft intraocular lens (IOL) implantation combined with viscogoniosynechialysis in the management of primary angle closure glaucoma (PACG). Methods Forty-six eyes of primary angle closure glaucoma with co-existing cataract were treated with phacoemulsification and IOL implantation combined with goniosynechialysis. The mean follow-up duration was 9 to 24 months. The main outcome measures were pre-operative and post-operative changes of intraocular pressure
visual acuity
depth of anterior chamber
anterior chamber angle
outflow facility of aqueous humor (C values) and PO/C ratio
and the number of glaucoma eye drops required. Results Compared with pre-operation
intraocular pressure was decreased (paired t test
P0.001)
visual acuity was improved (P0.01)
depth of anterior chamber was deepened (paired t test
P0.001) and anterior chamber angle of 36 eyes (78.26%) was open
outflow facility of aqueous humor (C values) and PO/C ratio were improved (paired t test
P0.01)
and the number of glaucoma eye drops required was decreased (paired t test
P0.01). Seven eyes (15.21%) had to undergo trabeculectomy because intraocular pressure was over 25 mmHg after phacoemulsification. Conclusion Phacoemulsification combined with viscogoniosynechialysis is an effective and safe surgical procedure in managing primary angle-closure glaucoma with co-existing cataract. However
trabeculectomy may be necessary for the cases with peripheral anterior synechia more than 270 degrees.
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