<sup>11</sup>C-胆碱PET在肺癌诊断与分期中的应用

张清; 刘阳; 张锦明; 张竞; 周乃康; 孙玉鹗

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¹¹C-胆碱PET在肺癌诊断与分期中的应用

论著 | 更新时间：2026-01-09

- ¹¹C-胆碱PET在肺癌诊断与分期中的应用
- ¹¹C-choline PET in diagnosis and staging of lung cancer: report of 54 cases
- 陆军军医大学学报 2008年30卷第23期页码：2233-2235
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  中图分类号： R734.2;R814.42;R981
- 纸质出版：2008
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张清,刘阳,张锦明,张竞,周乃康,孙玉鹗.11C-胆碱PET在肺癌诊断与分期中的应用[J].陆军军医大学学报(原第三军医大学学报),2008,30(23):2233-2235.

　ZHANG Qing,LIU Yang,ZHANG Jin-ming,ZHANG Jing,ZHOU Nai-kang,SUN Yu-e.11C-choline PET in diagnosis and staging of lung cancer: report of 54 cases[J].J Amry Med Univ (J Third Mil Med Univ),2008,30(23):2233-2235.
张清,刘阳,张锦明,张竞,周乃康,孙玉鹗.11C-胆碱PET在肺癌诊断与分期中的应用[J].陆军军医大学学报(原第三军医大学学报),2008,30(23):2233-2235. DOI：

　ZHANG Qing,LIU Yang,ZHANG Jin-ming,ZHANG Jing,ZHOU Nai-kang,SUN Yu-e.11C-choline PET in diagnosis and staging of lung cancer: report of 54 cases[J].J Amry Med Univ (J Third Mil Med Univ),2008,30(23):2233-2235. DOI：

摘要

目的探讨

C-胆碱PET在肺癌诊断方面的灵敏度、特异度、准确度，以及在肺癌纵隔淋巴结转移灶检测方面的应用价值。方法 54例临床拟诊为肺癌的患者，经CT检查见肺部阴影，行

C-胆碱PET扫描，手术切除的标本经病理学检查，对照CT、

C-胆碱PET及病理学在肺部阴影病灶的诊断方面的结果。结果对肺癌原发灶探测，

C-胆碱PET显像总体灵敏度为77.27%，特异度为70.00%，准确度为75.93%，如除外肺泡癌则灵敏度为91.43%，特异度为70.00%，准确度为86.67%。在纵隔淋巴结转移检测方面，

C-胆碱PET的灵敏度、特异度及准确度分别为87.50%、91.43%、95.20%。从淋巴结分组情况来看，CT检查的灵敏度为47.37%（18/38），

C-胆碱PET显像灵敏度为86.84%（33/38）。结论

C-胆碱PET显像在肺癌（肺泡癌除外）诊断以及在纵隔淋巴结转移灶检测方面有很高的价值，与CT相比有较高的灵敏度，优越性显著，是肺癌临床分期的良好参照。

Abstract

Objective To investigate the application of

C-choline PET in the diagnosis and staging of lung cancer. Methods Fifty-four patients who were verified with pulmonary shadows by CT scanning received

C-choline PET in which standardized uptake values (SUVs) were used to evaluate the lesions. The results were compared with pathological data. Results ① For detecting of the primary lung cancer tumors

C-choline PET had a sensitivity of 77.27%

a specificity of 70.00%

and an accuracy o

f 75.93%. If the cases of alveolar carcinoma were excluded

these values were 91.43%

70.00% and 86.67%

respectively. ② For detecting the mediastinal lymph node metastases

the above-mentioned values of

C-choline PET were 87.50%

91.43% and 95.20% respectively. Compared with the data of pathological examination

the sensitivity of CT and

C-choline PET were 47.37% (18/38) and 86.84% (33/38) respectively in the detection of lymph nodes. Conclusion

C-choline PET is very useful in evaluating lung cancer (excluding the alveolar carcinoma) on the diagnosis and clinical staging. For the detection of mediastinal lymph node metastases

C -choline PET is superior to CT.

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11C-胆碱PET在肺癌诊断与分期中的应用

11C-choline PET in diagnosis and staging of lung cancer: report of 54 cases

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摘要

Abstract

关键词

Keywords

references

¹¹C-胆碱PET在肺癌诊断与分期中的应用

¹¹C-choline PET in diagnosis and staging of lung cancer: report of 54 cases