脑胶质瘤的磁共振弥散张量成像研究

张冬; 廖翠薇; 舒通胜; 邹利光; 王文献; 孙清荣; 戴书华; 杨春燕

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脑胶质瘤的磁共振弥散张量成像研究

论著 | 更新时间：2026-01-09

- 脑胶质瘤的磁共振弥散张量成像研究
- Diffusion tensor imaging analysis of glioma
- 陆军军医大学学报 2008年30卷第16期页码：1496-1498
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  中图分类号： R445.2;R739.41;R814.3
- 纸质出版：2008
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张冬,廖翠薇,舒通胜,邹利光,王文献,孙清荣,戴书华,杨春燕.脑胶质瘤的磁共振弥散张量成像研究[J].陆军军医大学学报(原第三军医大学学报),2008,30(16):1496-1498.

　ZHANG Dong,LIAO Cui-wei,SHU Tong-sheng,ZOU Li-guang,WANG Wen-xian,SUN Qing-rong,DAI Shu-hua,YANG Chun-yan.Diffusion tensor imaging analysis of glioma[J].J Amry Med Univ (J Third Mil Med Univ),2008,30(16):1496-1498.
张冬,廖翠薇,舒通胜,邹利光,王文献,孙清荣,戴书华,杨春燕.脑胶质瘤的磁共振弥散张量成像研究[J].陆军军医大学学报(原第三军医大学学报),2008,30(16):1496-1498. DOI：

　ZHANG Dong,LIAO Cui-wei,SHU Tong-sheng,ZOU Li-guang,WANG Wen-xian,SUN Qing-rong,DAI Shu-hua,YANG Chun-yan.Diffusion tensor imaging analysis of glioma[J].J Amry Med Univ (J Third Mil Med Univ),2008,30(16):1496-1498. DOI：

摘要

目的探讨磁共振弥散张量成像(diffusion tensor imaging

DTI)研究脑胶质瘤的价值。方法 20例经病理证实的脑胶质瘤患者，行磁共振弥散张量成像检查，在平均ADC图和FA图上分别测量瘤周水肿区、肿瘤实质区、脑脊液及对侧正常大脑白质区的平均ADC值和FA值。对照分析高级别组与低级别组胶质瘤之间平均ADC值和FA值的差异。结果肿瘤周围水肿区域的平均ADC值较肿瘤实质区、对侧大脑白质升高（P0.05)，较脑脊液降低（P0.05)；而FA值较脑脊液、肿瘤实质区升高（P0.05)，较对侧大脑白质降低（P0.05)。肿瘤实质区域的平均ADC值较脑脊液降低（P0.05)，较对侧正常脑白质升高（P0.05)；而FA值较脑脊液升高（P0.05)，较对侧大脑白质降低（P0.05)。高度恶性组和低度恶性组胶质瘤之间，实质区平均ADC值差异有统计学意义（P0.05)，而FA值差异无统计学意义（P0.05)。结论磁共振弥散张量成像对定量分析大脑胶质瘤及其与白质纤维束的关系有重要价值。

Abstract

Objective To explore the value of diffusion tensor imaging (DTI) in analyzing glioma. Methods Twenty patients with glioma received DTI examination. The average ADC value and FA values in the area of lesion

peritumoral edema

cerebrospinal fluid and white matter on the opposite side were measured and compared between high-grade glioma and low-grade glioma. Results There were significant statistical differences of average ADC value and FA value among the area of peritumoral edema and the area of lesion

cerebrospinal fluid and white matter in the opposite side. The average ADC and FA values in the area of lesion were significantly different from those in the area of cerebrospinal fluid and white matter on the opposite side. Significant statistical differences of the average ADC values other than FA values were observed between the malignant and the benign gliomas. Conclusion It is helpful to employ DTI to analyze glioma and its association with white matter fiber.

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