Objective  To evaluate the characteristics of fusion by using biomimetic nano-hydroxyapatite and ployamide66 composites (n-HA/PA66) interbody cage.   Methods  Thirty adult female goats underwent c3-4 discectomy and intervertebral fusion with n-HA/PA66 interbody cage (n=15) or autogenous iliac crest bone graft (n=15). CT scanning was performed at 4th

12th and 24th week after surgery to evaluate fusion. After the goats were killed respectively on the 12th and 24th week

nondestructive biomechanical test for stiffness

undecalcified histology were performed.   Results  The goats receiving n-HA/PA66 or autograft all showed complete fusion at 24th week

without statistically significant differience upon biomechanics

radiography and histomorphology (P0.05).    Conclusion  The intervertebral fusion cage of n-HA/PA66 has good biocompatibility and osteo-conductibility. It may be the ideal interbody fusion cage.