PENG Bin,LI Hui-zhi,YI Dong.Mining inter-transaction association rules from time series microarray data[J].J Amry Med Univ (J Third Mil Med Univ),2008,30(05):396-398.
PENG Bin,LI Hui-zhi,YI Dong.Mining inter-transaction association rules from time series microarray data[J].J Amry Med Univ (J Third Mil Med Univ),2008,30(05):396-398.DOI:
Objective To deduce the interactions between genes from time series microarray data. Methods We used inter-transaction association rules mining technique and GO (Gene Ontology) annotation to analyze the microarray data. Results Using 2-fold-change method
119 differential expression genes were identified from total 10 080 genes or ESTs
whose expression levels varied significantly on 6 periods of fetus cerebellar development. As a result
about 1 300 intertransaction association rules were extracted and 10 top rules were kept for their maximum J-measure values. A genes association network graph was deduced based on the 10 top rules. Conclusion Inter-transaction association rules are able to deduce the interactions between genes from time series microarray data and the gene expression status can be predicted based on the association rules.