Objective    To observe the effect of chronic emotional stress on ovarian function in rats.     Methods    The uncertain empty bottle stress was used as a source of emotional stress

and 20 day stress was carried out in 20 female SD rats aged 3 months. Another 20 rats were used as controls. The behavior changes and estrous cycle were observed. The serum levels of FSH

LH

E

2

and P were determined.      Results    The chronic emotional stress could increase attacking behavior and splenic index significantly (P0.01)

and prolong the estrous cycle significantly (P0.01)

but had no influence on ovarian index (P0.05). It could decrease serum FSH

LH and E

2

levels significantly (P0.01)

but had no effect on P levels (P0.05).     Concl

usion    The chronic emotional stress can influence the ovarian endocrine secretion in rats. This model may be used to study the influence of chronic emotional stress on generative endocrine secretion.