10例中国正常汉族人不同的汉语听觉任务时fMRI中Wernicke区激活的特点

吴南; 王健; 谢兵; 朱刚; 陈志; 吴国材; 冯华

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10例中国正常汉族人不同的汉语听觉任务时fMRI中Wernicke区激活的特点

论著 | 更新时间：2026-01-09

- 10例中国正常汉族人不同的汉语听觉任务时fMRI中Wernicke区激活的特点
- Characteristics of Wernicke area activiation in different listening tasks of Chinese: an fMRI research
- 陆军军医大学学报 2007年29卷第10期页码：985-987
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  中图分类号： R338.3;R339.16;R445.2
- 纸质出版：2007
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吴南,王健,谢兵,朱刚,陈志,吴国材,冯华.10例中国正常汉族人不同的汉语听觉任务时fMRI中Wernicke区激活的特点[J].陆军军医大学学报(原第三军医大学学报),2007,29(10):985-987.

　WU Nan,WANG Jian,XIE Bing,ZHU Gang,CHEN Zhi,WU Guo-cai,FENG Hua.Characteristics of Wernicke area activiation in different listening tasks of Chinese: an fMRI research[J].J Amry Med Univ (J Third Mil Med Univ),2007,29(10):985-987.
吴南,王健,谢兵,朱刚,陈志,吴国材,冯华.10例中国正常汉族人不同的汉语听觉任务时fMRI中Wernicke区激活的特点[J].陆军军医大学学报(原第三军医大学学报),2007,29(10):985-987. DOI：

　WU Nan,WANG Jian,XIE Bing,ZHU Gang,CHEN Zhi,WU Guo-cai,FENG Hua.Characteristics of Wernicke area activiation in different listening tasks of Chinese: an fMRI research[J].J Amry Med Univ (J Third Mil Med Univ),2007,29(10):985-987. DOI：

摘要

目的筛选能够在功能性核磁共振造影（functional magnetic resonance imaging

fMRI)上稳定激活Wernicke区的汉语听觉任务刺激模式。方法选用正常右利手中国汉族人10例，采用组块设计，应用西门子SONATA 1.5T MRI分别进行不同的汉语语言听觉刺激任务下的脑功能成像，汉语语言听觉刺激任务分2组：词汇理解组、段落理解组。同时以音乐组作为单纯听觉刺激对照。图像资料经处理后获得脑区激活图。结果音乐组可见双侧颞横回激活，激活以右侧颞叶为主；词汇理解组与段落理解组10例均可见以左颞叶为主的激活（Wernicke区），其中段落理解组激活信号更加强烈，时间-信号强度动态曲线稳定。结论汉语的段落理解任务可以作为临床观察fMRI中激活Wernicke区的听觉语言任务刺激模式。

Abstract

Objective To determine which listening task can activate Wernicke area steadily in fMRI. Methods In this study

blood oxygenation level dependent (BOLD)-fMRI was successfully performed at a field strength of 1.5T (SONATA). We selected 10 normal right-handed people and block design was used. There were 3 groups according to different listening tasks: music group

word comprehension group

paragraph comprehension group. Brain activation map was obtained after data postprocessing. Results Right temporal lobe activiation was observed in music group. We found activiation located mainly in left temporal lobe (Wernicke) of all cases in word comprehension group and paragraph comprehension group

and the signals were more clear and steady in paragraph comprehension group. Conclusion Paragraph comprehension task in Chinese can activate the Wernicke area steadily in fMRI.

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