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纸质出版:2007
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桂君民,王一.伴脉络膜脱离的原发性孔源性视网膜脱离术前局部和全身应用皮质类固醇激素效果比较[J].陆军军医大学学报(原第三军医大学学报),2007,29(11):1105-1107.
GUI Jun-min,WANG Yi.Comparison of ocular intensive and systemic corticosteroid administration prior to vitrectomy for primary rhegmatogenous retinal detachment with choroidal detachment[J].J Amry Med Univ (J Third Mil Med Univ),2007,29(11):1105-1107.
桂君民,王一.伴脉络膜脱离的原发性孔源性视网膜脱离术前局部和全身应用皮质类固醇激素效果比较[J].陆军军医大学学报(原第三军医大学学报),2007,29(11):1105-1107. DOI:
GUI Jun-min,WANG Yi.Comparison of ocular intensive and systemic corticosteroid administration prior to vitrectomy for primary rhegmatogenous retinal detachment with choroidal detachment[J].J Amry Med Univ (J Third Mil Med Univ),2007,29(11):1105-1107. DOI:
目的 比较伴脉络膜脱离的原发性孔源性视网膜脱离玻璃体手术前局部和全身应用皮质类固醇激素治疗的手术成功率和视功能改变。 方法 连续观察38例38眼原发性孔源性视网膜脱离伴脉络膜脱离并行玻璃体手术治疗患者。其中局部应用激素组(A组)11例,术前应用醋酸强的松龙眼液点眼每小时1次,用药(4.91±1.51) d;全身激素治疗组(B组)27例,术前地塞米松静脉滴注15 mg,3 d后剂量递减,术前用药(5.67±1.88)d。 结果 一次手术视网膜脱离复位率A组为54.5%,B组为63.0%;再次手术成功率A组为80.0%,B组为100%。 A组70%患者术后视力提高,20%视力保持不变,B组68%患者术后视力提高,24%视力保持不变。初次手术后视网膜脱离复发的15例患者中,14例系因玻璃体视网膜增殖形成所致。 结论 伴脉络膜脱离的原发性孔源性视网膜脱离玻璃体手术前局部激素治疗组的手术成功率趋势上低于全身激素治疗组。两组的最终视功能改善结果无差异。术后视网膜脱离复发的主要原因系玻璃体视网膜增殖所致。
Objective To compare the anatomic and functional results of ocular intensive and systemic corticosteroid administration prior to vitrectomy for primary rhegmatogenous retinal detachment with choroidal detachment. Methods A retrospective
clinical pilot study. Results Of 38 cases of primary rhegmatogenous retinal detachment with choroidal detachment
11 cases received intensive 1% prednisolone acetate eyedrops once each hour
totally 16 times a day (Group A) for (4.91±1.51) days and 27 cases received systemic corticosteroid treatment which is performed as intravenous injection of 15 mg Dexamethasone for 3 d and then taped down for (5.67±1.88) days prior to vitrectomy (Group B). The rate of anatomic reattachment by one operation was 54.5% for Group A and 63.0% for Group B; The rate of reattachment by reoperation was 80% for Group A and 100% for Group B. The functional result was the same in the two groups
with the vision improvement in 70% cases of Group A and 68% cases of Group B. The minimal follow-up period was 3 months after final operation. Conclusion There is an obvious tendence of lower rate of anatomic reattachment in intensive steroid eyedrops treatment group than in systemic corticosteroid treatment group. However
the functional result is almost the same in the two groups.
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