Objective     To explore the inchoate changes in patients with Graves disease (GD) treated with

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I and appraise the therapeutic effect.      Methods     According to the thyroid size

patients’ age

thyroid

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I intake rate and course of the disease

303 patients with GD were given individual

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I doses. Six months later

the symptom

signs

and thyroid hormone levels of every case were compared with those recorded before.      Results     The symptom and the level of thyroid hormones were significantly meliorated after

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I  treatment. Six cases became goggle-eyed after treatment. Among the 303 patients

249(82.18%) fully recovered

21 (6.93%) partially remitted

24(7.92%) developed

hypothyroidism

and 9(2.97%) showed ineffective.      Conclusion     

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I treatment for GD with an individual dose can exert a satisfied therapeutic efficacy. It may as serve the first choice for GD treatment.