JIN Jie,CHEN Jing,YAN Zhen-cheng.Insulin resistance in essential hypertension patients and effect of imidapril on it[J].J Amry Med Univ (J Third Mil Med Univ),2007,29(13):1343-1344.
JIN Jie,CHEN Jing,YAN Zhen-cheng.Insulin resistance in essential hypertension patients and effect of imidapril on it[J].J Amry Med Univ (J Third Mil Med Univ),2007,29(13):1343-1344.DOI:
Objective To certify insuline resistance in nonobese patients with essential hypertension (EH) and observe effect of imidapril. Methods An oral glucose tolerance test (OGTT) and insulin releasing test (IRT) were performed on 40 nonobese EH patients before and after imidapril treatment
the plasma levels of glucose and insulin were tested and compared with those of 16 normal subjects. Results The insuline level of fasting or 30
60
120 min after OGTT were significantly higher than those in normal group (P0.05). After 8-week imidapril treatment
the fasting insulin level decreased
and 30-minute
60-minute insuline level after OGTT decreased more (P0.05). Conclusion There is insuline resistance in EH patients and imidapril can improve it.