Construction of a quality control index system for intravenous medication admixture

WANG Gancheng; DU Yawei; CHENG Yinchu; ZHAO Rongsheng

doi:10.6039/j.issn.1001-0408.2026.05.02

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Construction of a quality control index system for intravenous medication admixture

更新时间：2026-03-10

- Construction of a quality control index system for intravenous medication admixture
- ZHONGGUO YAOFANG Vol. 37, Issue 5, Pages: 559-564(2026)
- 作者机构：
  
  1.北京大学第三医院药学部，北京　100191
  2.北京大学药学院药事管理与临床药学系，北京　100191
- 作者简介：
- 基金信息：
- DOI：10.6039/j.issn.1001-0408.2026.05.02
  CLC： R95
- Received：02 December 2025，
  
  Revised：2026-02-11，
  
  Accepted：11 February 2026，
  
  Published：15 March 2026
- 稿件说明：
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王干城,杜雅薇,程吟楚,等.静脉用药调配质量控制指标体系的构建 ^Δ[J].中国药房,2026,37(05):559-564.

WANG Gancheng,DU Yawei,CHENG Yinchu,et al.Construction of a quality control index system for intravenous medication admixture[J].ZHONGGUO YAOFANG,2026,37(05):559-564.
王干城,杜雅薇,程吟楚,等.静脉用药调配质量控制指标体系的构建 ^Δ[J].中国药房,2026,37(05):559-564. DOI： 10.6039/j.issn.1001-0408.2026.05.02.

WANG Gancheng,DU Yawei,CHENG Yinchu,et al.Construction of a quality control index system for intravenous medication admixture[J].ZHONGGUO YAOFANG,2026,37(05):559-564. DOI： 10.6039/j.issn.1001-0408.2026.05.02.

摘要

目的

构建科学、系统的静脉用药调配质量控制指标体系，以保障患者用药安全与提升医疗服务质量。

方法

在文献分析和横断面调查研究基础上，初步拟定指标框架，并通过两轮德尔菲专家咨询收集意见，计算专家权威系数与肯德尔协调系数评估一致性；最终采用层次分析法确定各指标权重并检验一致性，以构建科学、系统的静脉用药调配质量控制指标体系。

结果

两轮函询专家积极系数均值为95.92%，权威系数均值为0.983。第二轮函询中，一、二、三级指标的肯德尔协调系数分别为0.306、0.440、0.394，均显著高于第一轮函询的0.211、0.274、0.379。最终构建的静脉用药调配质量控制指标体系包含6个一级指标（人员、药品耗材、设施设备、流程管理、环境卫生、成效）、17个二级指标（如教育培训、结构与梯队、工作强度、药品管理、耗材管理、设施设备管理等）、44个三级指标（如人均日工作量、药学专业技术人员占比、工作能力考核合格率、工作制度考核合格率、继续教育频次与考核合格率、药品账物相符率等）。

结论

本研究构建的静脉用药调配质量控制指标体系具有良好权威性与科学性，可为医院静脉用药调配质量的规范化管理提供理论依据与实践工具。

Abstract

OBJECTIVE

To construct a scientific and systematic quality control index system for intravenous medication admixture， so as to ensure the safety of drug use and improve the quality of medical service.

METHODS

Based on literature analysis and cross-sectional survey， an initial indicator framework was formulated. Opinions were then gathered through two rounds of Delphi expert consultations， and the expert authority coefficient and Kendall’s coefficient of concordance were calculated to evaluate the consistency. Ultimately， the analytic hierarchy process was employed to determine the weights of each indicator and test for consistency in order to establish a scientific and systematic quality control indicator system for intravenous medication admixture.

RESULTS

The study conducted two rounds of expert consultation with an average positive coefficient of 95.92% and an average authority coefficient of 0.983. In the second round of the Delphi consultation， the Kendall’s coefficients of concordance for the first-， second-， and third-level indicators were 0.306， 0.440， and 0.394， respectively， all significantly higher than those in the first round （0.211， 0.274， 0.379）. The final quality control system for intravenous medication admixture consisted of 6 first-level indicators （personnel， medicines and consumables， facilities and equipment， process management， environmental hygiene， and outcomes）， 17 second-level indicators （e.g.， education and training， staffing structure， workload， medication management， consumables management， and equipment maintenance）， and 44 third-level indicators （e.g.， average daily workload per person， proportion of pharmacy professionals， competency assessment pass rate， work system assessment pass rate， continuing education frequency and pass rate， and medication inventory accuracy）.

CONCLUSIONS

The quality control system for intravenous medication admixture developed in this study demonstrates strong authority and scientific rigor， providing a theoretical basis and practical tool for the standardized management of intravenous medication admixture quality in hospitals.

关键词

Keywords

references

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