BAO Jianing,ZHANG Xiaonan,TAO Xufeng,et al.Research progress on anti-inflammatory effects of traditional Chinese medicine under the guidance of syndrome differentiation and treatment[J].ZHONGGUO YAOFANG,2026,37(04):528-532.
BAO Jianing,ZHANG Xiaonan,TAO Xufeng,et al.Research progress on anti-inflammatory effects of traditional Chinese medicine under the guidance of syndrome differentiation and treatment[J].ZHONGGUO YAOFANG,2026,37(04):528-532. DOI: 10.6039/j.issn.1001-0408.2026.04.20.
Research progress on anti-inflammatory effects of traditional Chinese medicine under the guidance of syndrome differentiation and treatment
Inflammation is the body’s response to damage, infection or other stimuli, but its excessive or continuous development can lead to a variety of diseases. Although modern medical anti-inflammatory therapies were widely used, it is often accompanied by limitations such as more adverse reactions. Based on the “holistic view” and “differential treatment”, traditional Chinese medicine (TCM) regards inflammation as a manifestation of the imbalance of yin and yang in the body and the conflict between good and evil. The application of anti-inflammatory TCM is not only aimed at the pathological state of “inflammation”, but also based on the overall consideration of “syndrome”. According to different types of syndrome, anti-inflammatory TCM can be divided into heat-clearing and detoxifying agents (such as
Lonicera japonica
and
Isatis indigotica
), heat-clearing and drying dampness agents (such as Coptidis Rhizoma), blood-activating and stasis-dissolving agents (such as
Salvia miltiorrhiza
) and vital qi-strengthening and pathogenic factor-expelling agents (such as
Panax ginseng
). Four types of anti-inflammatory TCM restore the body’s immune balance through the systematic regulation of multi-component, multi-target and multi-pathway, exhibiting a good anti-inflammatory effect. Future research should focus on integrating systematic biology, applying artificial intelligence, carrying out high-quality evidence-based research, and combining traditional Chinese medicine and Western medicine, so as to reveal the overall regulatory law of anti-inf
lammatory effects of TCM and promote clinical rational use.
关键词
Keywords
references
WANG K J , YIN J , CHEN J Y , et al . Inhibition of inflammation by berberine:molecular mechanism and network pharmacology analysis [J ] . Phytomedicine , 2024 , 128 : 155258 .
TORRES-ROSAS R , YEHIA G , PEÑA G , et al . Dopamine mediates vagal modulation of the immune system by electroacupuncture [J ] . Nat Med , 2014 , 20 ( 3 ): 291 - 295 .
SUN J , ZHANG Q , YANG G , et al . The licorice flavonoid isoliquiritigenin attenuates Mycobacterium tuberculosis -induced inflammation through Notch1/NF-κB and MAPK signaling pathways [J ] . J Ethnopharmacol , 2022 , 294 : 115368 .
LI Y , WAN C , LI F , et al . Indirubin attenuates sepsis by targeting the EGFR/SRC/PI3K and NF-κB/MAPK signaling pathways in macrophages [J ] . Front Pharmacol , 2025 , 16 : 1542061 .
XIANG X L , LYU J , DONG M Y , et al . Radix Isatidis polysaccharide(RIP) resists the infection of QX-type infectious bronchitis virus via the MDA5/TLR3/IRF7 signaling pathway [J ] . Poult Sci , 2023 , 102 ( 4 ): 102534 .
LI J L , DAN W C , ZHANG C C , et al . Exploration of berberine against ulcerative colitis via TLR4/NF-κB/HIF-1α pathway by bioinformatics and experimental validation [J ] . Drug Des Devel Ther , 2024 , 18 : 2847 - 2868 .
XUE Y , FU W , LIU Y , et al . Ginsenoside Rb 2 alleviates myocardial ischemia/reperfusion injury in rats through SIRT1 activation [J ] . J Food Sci , 2020 , 85 ( 11 ): 4039 - 4049 .