Development and evaluation of classification system for drug-related problems in China

ZOU Shuang; LU Tingting; BAO Lei; LIAO Yun; LI Ling; ZHANG Ping

doi:10.6039/j.issn.1001-0408.2026.03.17

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Development and evaluation of classification system for drug-related problems in China

更新时间：2026-02-11

- Development and evaluation of classification system for drug-related problems in China
- ZHONGGUO YAOFANG Vol. 37, Issue 3, Pages: 371-376(2026)
- 作者机构：
  
  1.上海交通大学医学院附属同仁医院药学部，上海　200336
  2.上海交通大学附属第一人民医院临床药学科，上海　200080
- 作者简介：
- 基金信息：
- DOI：10.6039/j.issn.1001-0408.2026.03.17
  CLC： R969.3
- Received：21 July 2025，
  
  Revised：2026-01-21，
  
  Accepted：21 January 2026，
  
  Published：15 February 2026
- 稿件说明：
移动端阅览
邹双,陆婷婷,鲍磊,等.中国药物相关问题分类系统的构建及评价 [J].中国药房,2026,37(03):371-376.

ZOU Shuang,LU Tingting,BAO Lei,et al.Development and evaluation of classification system for drug-related problems in China[J].ZHONGGUO YAOFANG,2026,37(03):371-376.
邹双,陆婷婷,鲍磊,等.中国药物相关问题分类系统的构建及评价 [J].中国药房,2026,37(03):371-376. DOI： 10.6039/j.issn.1001-0408.2026.03.17.

ZOU Shuang,LU Tingting,BAO Lei,et al.Development and evaluation of classification system for drug-related problems in China[J].ZHONGGUO YAOFANG,2026,37(03):371-376. DOI： 10.6039/j.issn.1001-0408.2026.03.17.

摘要

目的

建立适用于我国药师在药学监护中使用的中国药物相关问题（DRP）分类系统，为药师提供一种有效、实用的药学监护工具。

方法

通过文献检索与分析、各分类系统对比、分类条目梳理与分类框架构建、两轮标准案例验证、专家讨论及分类系统修订等多阶段过程构建中国DRP分类系统；采用标准Fleiss′ kappa检验计算一致性系数

，评估参与验证的药师在评价该分类系统时的可信度；采用包含6个项目的电子问卷调查评估该分类系统的适用性。

结果

构建的中国DRP分类系统包含6个部分[问题（包括潜在的问题）、DRP评价、原因（包括潜在问题的可能原因）、介入方案、介入方案接受、DRP状态

]

，共设24个一级编码和96个二级编码。第一轮案例验证中，除了“介入方案”和“DRP状态”部分，其余部分的

值均大于0.4；第二轮案例验证中，各部分的

值均大于0.4。分类系统适用性评价中，验证药师对各项目的积极评分（“非常同意”或“同意”）占比均超过85%。其中，“分类系统可提供合适的类别选择”“分类系统比较全面”“分类系统使用方便”及“对该分类系统比较满意”4项的积极评分占比超过92%。

结论

构建的中国DRP分类系统的可信度和适用性均较好，可为中国药师开展药学监护提供一种有效、实用的分类工具。

Abstract

OBJECTIVE

To establish a Chinese drug-related problem （DRP） classification system applicable to pharmacist-led pharmaceutical care in China， providing pharmacists with an effective and practical tool for pharmaceutical care.

METHODS

A multi-stage process was employed to construct the DRP classification system， including literature review and analysis， comparison of existing classification systems， refinement of classification items and framework development， two rounds of standard case validation， expert discussion， and system revision. The Fleiss′ kappa test was used to calculate the consistency coefficient

， assessing the reliability of pharmacists participating in evaluating the classification system. An electronic questionnaire comprising six items was employed to evaluate the system’s applicability.

RESULTS

The constructed Chinese DRP classification system comprised six sections [problem（including potential problems）， DRP evaluation， cause （including possible causes of potential problems）， intervention， acceptance of intervention and DRP status

]

， with 24 primary codes and 96 secondary codes. In the first round of case validation，

values exceeded 0.4 for all sections except “intervention” and “DRP status”. In the second round，

values exceeded 0.4 for all sections. In the applicability evaluation of the classification system， positive ratings （“strongly agree” or “agree”） exceeded 85% for all items. Specific

ally， positive ratings for“the classification system can provide appropriate category selection”， “the classification system is comprehensive”， “the classification system is convenient to use” and “the classification system is highly satisfactory” exceeded 92%.

CONCLUSIONS

The Chinese DRP classification system developed demonstrates both high reliability and applicability， providing an effective and practical classification tool for pharmacists in China to conduct pharmaceutical care.

关键词

Keywords

references

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