Construction of the research questions and topic selection evaluation index system of <italic style="font-style: italic">Guideline for Topic Selection for Comprehensive Clinical Evaluation of Drugs </italic>based on Delphi method and analytic hierarchy process

DUAN Rong; LI Zhengxiang

doi:10.6039/j.issn.1001-0408.2025.07.04

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Construction of the research questions and topic selection evaluation index system of Guideline for Topic Selection for Comprehensive Clinical Evaluation of Drugs based on Delphi method and analytic hierarchy process

更新时间：2025-09-23

- Construction of the research questions and topic selection evaluation index system of Guideline for Topic Selection for Comprehensive Clinical Evaluation of Drugs based on Delphi method and analytic hierarchy process
- ZHONGGUO YAOFANG Vol. 36, Issue 7, Pages: 789-793(2025)
- 作者机构：
  
  天津医科大学总医院药剂科，天津　300052
- 作者简介：
- 基金信息：
- DOI：10.6039/j.issn.1001-0408.2025.07.04
  CLC： R95
- Received：31 October 2024，
  
  Revised：2025-02-15，
  
  Accepted：17 February 2025，
  
  Published：15 April 2025
- 稿件说明：
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段蓉,李正翔.基于德尔菲法和层次分析法构建《药品临床综合评价主题遴选指南》研究问题及主题遴选评估指标体系 [J].中国药房,2025,36(07):789-793.

DUAN Rong,LI Zhengxiang.Construction of the research questions and topic selection evaluation index system of Guideline for Topic Selection for Comprehensive Clinical Evaluation of Drugs based on Delphi method and analytic hierarchy process[J].ZHONGGUO YAOFANG,2025,36(07):789-793.
段蓉,李正翔.基于德尔菲法和层次分析法构建《药品临床综合评价主题遴选指南》研究问题及主题遴选评估指标体系 [J].中国药房,2025,36(07):789-793. DOI： 10.6039/j.issn.1001-0408.2025.07.04.

DUAN Rong,LI Zhengxiang.Construction of the research questions and topic selection evaluation index system of Guideline for Topic Selection for Comprehensive Clinical Evaluation of Drugs based on Delphi method and analytic hierarchy process[J].ZHONGGUO YAOFANG,2025,36(07):789-793. DOI： 10.6039/j.issn.1001-0408.2025.07.04.

摘要

目的

构建《药品临床综合评价主题遴选指南》研究问题及主题遴选评估指标体系，为该指南的制定提供依据。

方法

通过文献研究，初步构建《药品临床综合评价主题遴选指南》研究问题及主题遴选评估指标体系专家问卷。根据指南制定和德尔菲法相关要求遴选专家，通过电子问卷函询并筛选指南研究问题及评估指标，采用层次分析法对主题遴选评估指标体系进行权重赋值。

结果

构建了5个《药品临床综合评价主题遴选指南》研究问题，包括主题遴选的组织管理、评审流程、评估方法、评估指标体系和指标权重赋值，并构建包括5个一级指标、9个二级指标、17个三级指标在内的主题遴选评估指标体系。研究问题及各级指标的肯德尔协调系数均大于0.4，

检验

值均小于0.05，评价结果具有较好的一致性。利用层次分析法对主题遴选评估指标体系的各级指标进行权重赋值，一致性比率为0.007 6（＜0.1），模型矩阵通过一致性检验。

结论

本研究构建的《药品临床综合评价主题遴选指南》的研究问题及主题遴选评估指标体系具有较高的权威性、科学性和可靠性，可为该指南的标准化制定奠定基础。

Abstract

OBJECTIVE

To construct the research questions and topic selection evaluation index system of the

Guideline for Topic Selection for Comprehensive Clinical Evaluation of Drugs

（hereinafter referred to as the

Guideline

）， so as to provide the basis for the formulation of the

Guideline

METHODS

Through literature research， an expert questionnaire on the research questions and evaluation index system of the

Guideline

was initially constructed. Experts were selected according to relevant requirements of the guideline formulation and Delphi method； the research questions and evaluation indicators of the

Guideline

were screened by electronic questionnaire communication， and the weights of evaluation index system of topic selection were assigned by the analytic hierarchy process.

RESULTS

Five research questions of the

Guideline

were constructed， including the organization and management of theme selection， evaluation process， evaluation methods， evaluation index system， and index weight assignment. And a th

eme selection and evaluation index system， including 5 primary indexes， 9 secondary indexes and 17 tertiary indexes， was constructed. Kendall coefficients of the research questions and all indexes were ＞0.4， and the

values of

test were＜0.05， which meant the evaluation results were consistent. The weights of all levels of the evaluation index system were assigned by analytic hierarchy process with consistency ratio of 0.007 6 （＜0.1）， and the model matrix passed the consistency test.

CONCLUSIONS

The research questions and topic selection evaluation index system of the

Guideline

established in this study are highly authoritative， scientific and reliable， which lay a foundation for the standardization of the

Guideline

关键词

Keywords

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Construction of the research questions and topic selection evaluation index system of Guideline for Topic Selection for Comprehensive Clinical Evaluation of Drugs based on Delphi method and analytic hierarchy process

DOI：10.6039/j.issn.1001-0408.2025.07.04

摘要

Abstract

关键词

Keywords

references