Quality analysis of <italic style="font-style: italic">Codonopsis pilosula</italic> with different commodity specification grades

ZHANG Xiaohui; TONG Liguo; WANG Yibing; LI Zhiqiang; XI Xiaohu; WANG Shuang; WANG Shiwei

doi:10.6039/j.issn.1001-0408.2023.11.15

您当前的位置：

首页 >

文章列表页 >

Quality analysis of Codonopsis pilosula with different commodity specification grades

更新时间：2025-09-27

- Quality analysis of Codonopsis pilosula with different commodity specification grades
- ZHONGGUO YAOFANG Vol. 34, Issue 11, Pages: 1363-1367(2023)
- 作者机构：
  
  1.山西省中医药研究院中心实验室，太原　030012
  2.长治医学院药学系，山西长治　046013
  3.山西省中医院药剂科，太原　030012
- 作者简介：
- 基金信息：
- DOI：10.6039/j.issn.1001-0408.2023.11.15
  CLC： R917;R282
- Received：20 November 2022，
  
  Revised：2023-01-03，
  
  Accepted：03 April 2023，
  
  Published：15 June 2023
- 稿件说明：
移动端阅览
张小慧,仝立国,王亦冰,等.不同商品规格等级党参药材的质量分析[J].中国药房,2023,34(11):1363-1367.

ZHANG Xiaohui,TONG Liguo,WANG Yibing,et al.Quality analysis of Codonopsis pilosula with different commodity specification grades[J].ZHONGGUO YAOFANG,2023,34(11):1363-1367.
张小慧,仝立国,王亦冰,等.不同商品规格等级党参药材的质量分析[J].中国药房,2023,34(11):1363-1367. DOI： 10.6039/j.issn.1001-0408.2023.11.15.

ZHANG Xiaohui,TONG Liguo,WANG Yibing,et al.Quality analysis of Codonopsis pilosula with different commodity specification grades[J].ZHONGGUO YAOFANG,2023,34(11):1363-1367. DOI： 10.6039/j.issn.1001-0408.2023.11.15.

摘要

目的

研究不同商品规格等级党参药材的质量，为该药材的市场流通、科研及临床使用提供依据。

方法

根据目前党参药材的商品规格等级划分标准，收集不同产地、基原、商品规格等级的党参药材共17批，采用高效液相色谱法测定党参苷Ⅰ、党参炔苷和白术内酯Ⅲ的含量，采用《中国药典》（四部）中醇溶性浸出物测定法（通则2201）项下“热浸法”测定其醇溶性浸出物的含量，采用苯酚硫酸法测定其多糖的含量（以D-无水葡萄糖计）。

结果

对于党参的栽培品种，4种规格3个商品等级的党参药材均含有党参苷Ⅰ和党参炔苷，潞党参、纹党参还含有白术内酯Ⅲ。党参苷Ⅰ、党参炔苷、白术内酯Ⅲ含量方面，栽培药材二等品与一等品含量相当，甚至优于一等品，三等品含量低于一等品、二等品；两种野生党参中党参苷Ⅰ含量最高。醇溶性浸出物和多糖含量方面，栽培药材一等品含量高于二等品，二等品含量高于三等品，野生党参含量较低。

结论

不同商品规格等级的党参药材栽培品种的内在质量和目前依据性状和基原的规格等级划分标准基本一致，一等药材与二等药材均有较高的指标成分含量，属优质药材。

Abstract

OBJECTIVE

To study the quality of

Codonopsis pilosula

with different commodity specification grades， and to provide the data support for market transactions， scientific research and clinical use.

METHODS

According to the classification standard of commodity specification grades of

C. pilosula

， 17 batches of

C. pilosula

from different producing areas， origins and commodity specification grades were collected. The contents of tangshenoside Ⅰ， lobetyolin and atractylenolide Ⅲ were determined by HPLC. The contents of alcohol-soluble extracts were determined by hot dipping method stated in general rule 2201 of

Chinese Pharmacopeia

（part Ⅳ）. The contents of polysaccharide were determined by phenol-sulfuric acid method （calculated by D-glucose anhydrous）.

RESULTS

For cultivar of

C. pilosula

， four specifications and three commodity grades of

C. pilosula

all contained tangshenoside Ⅰ and lobety

olin； Radix

C. pilosula

from Shanxi of China and

C. pilosula

from Wenxian County of China， also contained atractylenolide Ⅲ. In terms of the contents of tangshenoside Ⅰ， lobetyolin and atractylenolide Ⅲ， the content of second class was equivalent to that of first class， even better than the first class， while the content of third class was lower than that of first class and second class； the content of tangshenoside Ⅰ was the highest among the two types of wild

C. pilosula

. The contents of alcohol-soluble extracts and polysaccharides in first class cultivated

C. pilosula

were higher than those of second class， and the second class was higher than the third class； wild

C. pilosula

had low content of alcohol-soluble extracts and polysaccharides.

CONCLUSIONS

The internal quality of

C. pilosula

is basically consistent with the classification standard of different commodity specification grades； the content of each indicator in first-class and second-class medicinal herb is high， making them high-quality medicinal herbs.

关键词

Keywords

references

李鹏英，王海洋，李健，等 . 中药材商品规格等级的形成和演变 [J ] . 中国中药杂志， 2016 ， 41 （ 5 ）： 764 - 768 .

黄璐琦，詹志来，郭兰萍 . 中药材商品规格等级标准汇编：第1辑 [M ] . 北京：中国中医药出版社， 2019 ： 71 - 78 .

谌勤，罗洪斌，谢文执 . 板桥党参通过PP2A信号通路改善AD模型大鼠认知功能障碍 [J ] . 中国药理学通报， 2019 ， 35 （ 9 ）： 1232 - 1239 .

陈少夫，贺丽，周卓，等 . 党参对兔胃十二指肠黏膜中胃泌素、生长抑素的影响 [J ] . 中国医科大学学报， 2002 ， 31 （ 3 ）： 164 - 165 .

钟灵 . 党参对心肌缺血/再灌注损伤家兔血流动力学和心肌酶的影响 [J ] . 中国老年学杂志， 2012 ， 32 （ 5 ）： 966 - 968 .

胡天惠，林超，项媛媛，等 . 潞党参口服液对免疫抑制小鼠的免疫调节作用 [J ] . 药学与临床研究， 2019 ， 27 （ 3 ）： 171 - 174，186 .

赵晓芳 . 板党多糖对溃疡性结肠炎大鼠的防治作用及机制研究 [D ] . 武汉：湖北中医药大学， 2016 .

高石曼 . 党参药材的质量评价及其免疫调节和造血改善的药效物质基础研究 [D ] . 北京：北京协和医学院， 2020 .

JI G Q ， CHEN R Q ， WANG L . Anti-inflammatory activity of atractylenolide Ⅲ through inhibition of nuclear factor-κB and mitogen-activated protein kinase pathways in mouse macrophages [J ] . Immunopharmacol Immunotoxicol ， 2016 ， 38 （ 2 ）： 98 - 102 .

董海燕，董亚琳，贺浪冲，等 . 白术抗炎活性成分的研究 [J ] . 中国药学杂志， 2007 ， 42 （ 14 ）： 1055 - 1059 .

罗兰，孙悦 . 白术内酯Ⅲ对神经细胞损伤的影响 [J ] . 时珍国医国药， 2012 ， 23 （ 3 ）： 560 - 562 .

于新宇，张媛媛，嵇志红 . 白术内酯Ⅲ对痴呆大鼠学习记忆能力及海马Bcl-2表达的影响 [J ] . 东北师大学报（自然科学版）， 2018 ， 50 （ 3 ）： 109 - 113 .

孙晓燕，蔡昌利，徐丽莉，等 . 多糖含量测定方法的比较 [J ] . 现代中药研究与实践， 2015 ， 29 （ 3 ）： 58 - 62 .

Views

417

下载量

CSCD

Alert me when the article has been cited

提交

Tools

Publicity Resources

Quality evaluation of Euscaphis japonica from different habitats using chemometrics combined with weighted TOPSIS model

Comprehensive evaluation of the quality of Yindan huoxue tongyu granules based on fingerprint combined with content of pharmacodynamic components

Quality evaluation of diagnosis and treatment guidelines and expert consensus for children with immune thrombocytopenic purpura

Optimization of particle forming process and quality evaluation of Yindan huoxue tongyu granules

Study on quality evaluation of Mongolian medicine Sanzi powder： fingerprint， chemical pattern recognition and multi-component quantification analysis

Related Author

GAO Yuqiu

ZHENG Shuai

YU Xue

ZOU Guihua

ZHANG Kai

BAI Shuxian

WANG Dandan

WU Zuomin

Related Institution

College of Pharmacy， Mudanjiang Medical University

First Clinical Medical College， Mudanjiang Medical University

Dept. of Pharmacy， Hongqi Hospital Affiliated to Mudanjiang Medical University

Dept. of Critical Care Medicine， Luohe Central Hospital

Dept. of Pharmacy， Luohe Central Hospital

⁰

Quality analysis of Codonopsis pilosula with different commodity specification grades

DOI：10.6039/j.issn.1001-0408.2023.11.15

摘要

Abstract

关键词

Keywords

references