Electrophysiological characteristics and clinical significance of unilateral tinnitus with normal hearing threshold

Wenjing WU; Zhendong JIANG; Fazhang LAN; Ya HE; Cheng ZHONG

doi:10.16016/j.2097-0927.202401124

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Electrophysiological characteristics and clinical significance of unilateral tinnitus with normal hearing threshold

Clinical Medicine | 更新时间：2026-01-09

- Electrophysiological characteristics and clinical significance of unilateral tinnitus with normal hearing threshold
- Journal of Army Medical University Vol. 46, Issue 17, Pages: 2016-2020(2024)
- 作者机构：
  
  400038 重庆，陆军军医大学(第三军医大学)第一附属医院耳鼻咽喉头颈外科
- 作者简介：
- 基金信息：
- DOI：10.16016/j.2097-0927.202401124
  CLC： R338.8;R339.16;R764.45
- Received：28 January 2024，
  
  Revised：2024-05-19，
  
  Published：15 September 2024
- 稿件说明：
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Wenjing WU, Zhendong JIANG, Fazhang LAN, et al. Electrophysiological characteristics and clinical significance of unilateral tinnitus with normal hearing threshold[J]. Journal of Army Medical University, 2024, 46(17): 2016-2020.
DOI：

Wenjing WU, Zhendong JIANG, Fazhang LAN, et al. Electrophysiological characteristics and clinical significance of unilateral tinnitus with normal hearing threshold[J]. Journal of Army Medical University, 2024, 46(17): 2016-2020. DOI： 10.16016/j.2097-0927.202401124.

摘要

目的

探究正常听阈单侧耳鸣患者电生理特征及临床意义。

方法

选取2022年5月至2023年2月陆军军医大学第一附属医院耳鼻咽喉头颈外科收治的34例听力正常主诉单侧耳鸣患者作为研究对象，以患侧组与健侧组检测数据进行对比。对患者双侧分别进行纯音听阈检测、畸变产物耳声发射(distortion product otoacoustic emissions

DPOAE)、听性脑干反应(auditory brainstem response，ABR)检测及扩展高频测听。

结果

ABR的波Ⅰ潜伏期患侧组较健侧组明显缩短，且差异具有统计学意义(1.60

1.73 ms

=0.018)。ABR的波Ⅰ幅值患侧组较健侧组明显下降(0.19

0.23 μV

=0.003)。患侧组34耳中波Ⅲ波幅大于波Ⅴ波幅有18耳(52.94%)，健侧组未发现波Ⅲ波幅大于波Ⅴ波幅，2组比较差异具有统计学意义(

=24.480，

0.001)。在12.5、14.0、16.0、18.0、20.0 kHz患侧组34耳扩展高频测听平均听阈值均高于健侧组，差异具有统计学意义(

0.05)。

结论

正常听阈主观性耳鸣者进行ABR检查可有助于初步判断听觉通路是否出现隐性功能改变，波Ⅰ幅值下降、波Ⅰ潜伏期缩短、波Ⅲ波幅大于波Ⅴ波幅等可作为客观参考指标。

Abstract

Objective

To investigate the electrophysiological characteristics and clinical significance of unilateral tinnitus with normal hearing threshold.

Methods

A total of 34 patients with normal hearing but unilateral tinnitus admitted to our department from May 2022 to February 2023 were recruited as the study subjects. Pure tone hearing threshold detection

distortion product otoacoustic emission (DPOAE)

auditory brainstem response (ABR) detection and extended high-frequency pure tone audiometry were performed on both ears (affected side and healthy side) of every patient. The data of the affected side group and those of healthy side group were compared.

Results

The Ⅰ-wave latency of ABR was significantly shorter (1.60

1.73 ms

=0.018)

and its amplitude was obviously decreased (0.19

0.23 μV

=0.003) in the affected side group when compared with the healthy side group. In the affected group (34 ears)

there were 18 ears (52.94%) having amplitude of wave Ⅲ greater than that of wave Ⅴ

while in the healthy group

no such difference in the amplitude between wave Ⅲ and wave Ⅴ was observed. There was statistical significance between the 2 groups (

Chi

-square=24.480

0.001). In the 12.5

14.0

16.0

18.0 and 20.0 kHz conditions

the average hearing threshold of extended high-frequency audiometry was all significantly higher in the affected side group than the healthy group (

0.05).

Conclusion

For subjective tinnitus patients with normal hearing threshold

ABR examination is helpful in preliminarily determining whether there are hidden functional changes in the auditory pathway. Decreased Ⅰ-wave amplitude

shortened Ⅰ-wave latency

and wave Ⅲ amplitude greater than wave Ⅴ amplitude can be used as objective reference indicators.

关键词

Keywords

references

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