1.400037 重庆,陆军军医大学(第三军医大学)第二附属医院血液病医学中心,全军临床重点专科,创伤与化学中毒全国重点实验室,重庆市临床重点专科,血液病与微环境重庆市重点实验室
2.401329 重庆,金凤实验室
Received:30 October 2023,
Revised:2023-12-22,
Published:28 February 2024
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Xi ZHANG. Precision diagnosis and treatment for hematological malignancies[J]. Journal of Army Medical University, 2024, 46(4): 299-310.
Xi ZHANG. Precision diagnosis and treatment for hematological malignancies[J]. Journal of Army Medical University, 2024, 46(4): 299-310. DOI: 10.16016/j.2097-0927.202310109.
目的
2
随着对血液肿瘤发病机制的深入研究
血液肿瘤的精准诊断和分层治疗逐年优化提升。近年来在人工智能的推动下
血液肿瘤诊断由人工化、经验化不断向智能化、信息化升级
在未来有望实现高效、高准确率的智能诊断; 同时
小分子药物、抗体类药物、免疫细胞治疗及造血干细胞移植新疗法在不断完善
新药不断涌现
为血液肿瘤的治疗提供了更多选择。本文从血液肿瘤的精准/智能诊断、药物治疗和细胞治疗等3个方面探讨血液肿瘤的精准诊断与治疗。
With the in-depth research on the pathogenesis of hematological malignancies
precision diagnosis and stratified treatment have been continuously enhanced and optimized over the years. In recent years
with the aid of artificial intelligence
the diagnosis of the malignancies has been upgraded from manual and empirical to intelligent and mechanized
and it is expected to realize intelligent diagnosis with high efficiency and high accuracy in the future. At the same time
the evolution of small molecule drugs
antibody drugs
immunotherapy and hematopoietic stem cell transplantation
and the emergence of new drugs expand the treatment options for hematological malignancies. In this article
we review the precision diagnosis and treatment of hematological tumors from 3 aspects: precision/intelligent diagnosis
medication
and cellular therapy.
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