Rapid visualization and detection of Cu<sup>2+</sup> in aqueous solution using high-resolution colorimetric probe

Hong TANG; Mo CHEN; Songling HAN

doi:10.16016/j.2097-0927.202307019

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Rapid visualization and detection of Cu²⁺ in aqueous solution using high-resolution colorimetric probe

Basic Medicine | 更新时间：2026-01-09

- Rapid visualization and detection of Cu²⁺ in aqueous solution using high-resolution colorimetric probe
- Journal of Army Medical University Vol. 45, Issue 21, Pages: 2239-2243(2023)
- 作者机构：
  
  1.400038 重庆，陆军军医大学(第三军医大学)军事预防医学系复合伤研究所
  2.400038 重庆，陆军军医大学(第三军医大学)创伤与化学中毒全国重点实验室
- 作者简介：
- 基金信息：
  
  the National Natural Science Foundation for Young Scholars of China(82003395)
- DOI：10.16016/j.2097-0927.202307019
  CLC： O614.121;R123.1;R446
- Received：04 July 2023，
  
  Revised：2023-07-20，
  
  Published：15 November 2023
- 稿件说明：
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Hong TANG, Mo CHEN, Songling HAN. Rapid visualization and detection of Cu²⁺ in aqueous solution using high-resolution colorimetric probe[J]. Journal of Army Medical University, 2023, 45(21): 2239-2243.
DOI：

Hong TANG, Mo CHEN, Songling HAN. Rapid visualization and detection of Cu²⁺ in aqueous solution using high-resolution colorimetric probe[J]. Journal of Army Medical University, 2023, 45(21): 2239-2243. DOI： 10.16016/j.2097-0927.202307019.

摘要

目的

构建特异性识别水中铜离子(Cu

)并快速显色的化学比色探针。

方法

基于BODIPY荧光染料设计合成Cu

比色探针BBSCP，紫外-可见光分光光度法评价探针对水中Cu

的显色能力，加入常见金属离子后评价比色探针的抗干扰能力。

结果

BBSCP在485~670 nm波长范围内表现出较宽的吸收带，加入Cu

后，在465~600 nm区间出现蓝移，波段变尖，而其他金属离子没有引起变化；同时在Cu

溶液中加入等当量的其他常见金属离子后仍然保持Cu

显色能力。

结论

构建的比色探针BBSCP对水溶液中Cu

具有高度敏感性和选择稳定性，能作为快速检测水中Cu

的可视化探针广泛应用于生物诊断、食品等多个领域。

Abstract

Objective

To develop a chemical colorimetric probe that specifically recognizes Cu

in water and then generates color rapidly.

Methods

colorimetric probe BBSCP was designed and synthesized based on BODIPY fluorescence dye

then its color rendering ability to Cu

in water was evaluated with UV visible spectrophotometry. After common metal ions were added into the Cu

solution

the anti-interference ability of the colorimetric probe were tested.

Results

Our developed BBSCP exhibits a wide absorption band in a range of 485 to 670 nm. After the addition of Cu

a blue shift was observed in the range of 465~600 nm

with sharper band

but no changes were found after other m

etal ions were added. At the same time

the color rendering ability of Cu

was maintained even after the addition of equivalent amounts of other common metal ions.

Conclusion

Our developed colorimetric probe BBSCP has high sensitivity and selective stability to Cu

in aqueous solution

and can be widely used as a visual probe for rapid detection of Cu

in water in various fields such as biological diagnosis and food.

关键词

Keywords

references

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Rapid visualization and detection of Cu2+ in aqueous solution using high-resolution colorimetric probe

DOI：10.16016/j.2097-0927.202307019

摘要

Abstract

关键词

Keywords

references

Rapid visualization and detection of Cu²⁺ in aqueous solution using high-resolution colorimetric probe