Epidemiological characteristics and trends of primary intussusception among children in Wuhan from 2016 to 2022

Hongxi GUO; Jun YANG; Hongiang BIAN; Hu YANG; Qin GUO

doi:10.16016/j.2097-0927.202303187

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Epidemiological characteristics and trends of primary intussusception among children in Wuhan from 2016 to 2022

Public Health and Preventive Medicine | 更新时间：2026-01-09

- Epidemiological characteristics and trends of primary intussusception among children in Wuhan from 2016 to 2022
- Journal of Army Medical University Vol. 45, Issue 19, Pages: 2085-2091(2023)
- 作者机构：
  
  430000 武汉，华中科技大学同济医学院附属武汉儿童医院(武汉市妇幼保健院)普外科
- 作者简介：
- 基金信息：
  
  the General Program of National Natural Science Foundation of China(81570466)
- DOI：10.16016/j.2097-0927.202303187
  CLC： R195.4;R725.743
- Received：31 March 2023，
  
  Revised：2023-05-06，
  
  Published：15 October 2023
- 稿件说明：
移动端阅览
Hongxi GUO, Jun YANG, Hongiang BIAN, et al. Epidemiological characteristics and trends of primary intussusception among children in Wuhan from 2016 to 2022[J]. Journal of Army Medical University, 2023, 45(19): 2085-2091.
DOI：

Hongxi GUO, Jun YANG, Hongiang BIAN, et al. Epidemiological characteristics and trends of primary intussusception among children in Wuhan from 2016 to 2022[J]. Journal of Army Medical University, 2023, 45(19): 2085-2091. DOI： 10.16016/j.2097-0927.202303187.

摘要

目的

探讨2016-2022年武汉地区原发性肠套叠(肠套叠)的流行病学特点及变化趋势。

方法

回顾性收集2016-2022年武汉儿童医院普外科收治的原发性肠套叠患儿的临床病历资料。采用描述性研究方法，分析近7年原发性肠套叠流行病学特征及变化趋势。

结果

7年间本院共收治原发性肠套叠患儿6 506例，其中男性4 457例，女性2 049例，男女比例约为2.18 ∶1。发病年龄为出生后2 d至12岁，年龄(23.56±18.03)个月，6~12月龄为高发年龄段，3岁以内占81.16%(5 280/6 506)；7月份发病例数最高。2016-2022年，年龄＜1岁原发性肠套叠患儿构成比由41.36%降至16.67%，而1~＜3岁年龄组构成比由43.80%增至56.28%，患儿年龄由(20.04±15.88)个月增至(30.37±20.30)个月。不同性别原发性肠套叠年龄分布的差异有统计学意义(

＜0.01)，年龄＜3岁时，女性构成比高于男性；年龄≥3岁后，男性构成比高于女性；不同性别原发性肠套叠季节及城乡分布的差异无统计学意义。腹部超声为主要影像学诊断方法(98.97%，6 439/6 506)。非手术为主要治疗方法(92.64%

6 027/6 506)，成功率92.25%(5 560/6 027)。376例(5.78%)肠套叠复发，其中1岁以上儿童占56.91%，初次发病后6个月内复发占75.27%。灌肠整复成功组及失败组在年龄和病程方面的差异均有统计学意义(

=0.024)。

结论

2016-2022年武汉地区儿童肠套叠平均患病年龄呈逐年递增趋势，＜1岁年龄组患儿构成比呈逐年递减趋势；儿童肠套叠的年龄分布与性别具有相关性；首次复发时间与年龄呈负相关；年龄越小、病程越长，灌肠失败率越高。

Abstract

Objective

To analyze the epidemiological characteristics and trend of primary intussusception in children in Wuhan from 2016 to 2022.

Methods

Clinical data of hospitalized children with primary intussusception admitted in our department from January 2016 to December 2022 were collected and retrospectively studied. Then descriptive research was performed to analyze the epidemiological characteristics and trend of primary intussusception in recent 7 years.

Results

A total of 6 506 children of primary intussusception were treated in our hospital during the past 7 years

including 4 457 boys and 2 049 girls

with a female-to-male ratio of 2.18 ∶1. They were at a mean age of 23.56±18.03 months (2 d~12 years). The disease was more common in an age of 6 to 12 months

and 81.16% (5 280/6 506) of the patients were under 3 years old. Most onset cases occurred in July. During 2016 and 2022

the constitution ratio of these children younger than 1 year old was decreased from 41.36% to 16.67%

while that of those aged 1-3 years was increased from 43.80% to 56.28%

and the average age of the patients was increased from 20.04±15.88 months to 30.37±20.30 months. Significant differences were observed in the age distributions between different genders (

0.01). For the patients aged

3 years

the girls took larger proportion

while the male patients covered larger proportion among those over 3 years old. There were no statistically differences in the seasonal and urban-rural distributions of the disease between different genders. Abdominal ultrasound examination was a major imaging method (98.97%

6 439/6 506). Non-surgical therapy was the majority of treatment (92.64%

6 027/6 506)

with a success rate of 92.25% (5 560/6 027). Recurrence occurred in 376 (5.78%) cases

56.91% of whom were younger than 1 years old

and among them

214 (75.27%) cases occurred within 6 months. But no statistical differences were observed in the age

distribution and disease course between the successful enema group and the failure group (

=0.024).

Conclusion

From 2016 to 2022

the average age of primary intussusception among children in the Wuhan region shows an increasing trend year by year

and the constitution ratio of the children younger than 1 year old is in a decreasing trend. For these children with primary intussusception

the age distribution is correlated with gender

and the time of first recurrence is negatively correlated with age. The younger the age and the longer the course of the disease

the higher the failure rate of enema reduction.

关键词

Keywords

references

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