1.510006 广州,广州中医药大学研究生院
2.510010 广州,中国人民解放军南部战区总医院康复科/重症康复中心
Received:11 March 2022,
Revised:2022-05-04,
Published:15 October 2022
移动端阅览
Xinwei YIN, Yong DAI, Huai HUANG, et al. Effect of progressive and step-up mobilization and exercise training on functional rehabilitation in critically ill patients: a prospective randomized controlled trail[J]. Journal of Army Medical University, 2022, 44(19): 1988-1995.
Xinwei YIN, Yong DAI, Huai HUANG, et al. Effect of progressive and step-up mobilization and exercise training on functional rehabilitation in critically ill patients: a prospective randomized controlled trail[J]. Journal of Army Medical University, 2022, 44(19): 1988-1995. DOI: 10.16016/j.2097-0927.202203100.
目的
2
探讨渐进性活动与运动进阶训练对重症患者功能康复的影响。
方法
2
通过随机数字表法将2019年9月1日至2021年9月1日在南部战区总医院重症监护病房、高依赖病房就诊的60例重症患者分为观察组与对照组,每组30例。两组患者均给予常规救治和护理,在此基础上,对照组接受常规运动康复训练,观察组开展被动、辅助、主动3个阶段的渐进性活动与运动进阶训练,为期6周。在训练前和训练6周后通过Fug1-Meyer评定量表下肢部分(Fugl-Meyer Assessment of Lower Extremity,FMA-LE)评估患者运动功能,改良Barthel量表(Modified Barthel Index,MBI)评估患者日常生活活动能力;分别在训练前,训练的第2、4和6周,应用徒手肌力评估量表(Medical Research Council Scale,MRC)和床旁膈肌超声评估肌肉功能。
结果
2
训练2周后,两组患者的肌力和膈肌移动度与其训练前相比皆下降,其中,对照组的下降程度更甚(
P
<
0.05);训练4周和6周后,两组患者肌力和膈肌移动度均得到改善(
P
<
0.05),观察组患者改善更加明显(
P
<
0.05);训练6周后,两组患者LE-FMA与MBI评分均较训练前提高(
P
<
0.05),且观察组显著高于对照组(
P
<
0.05)。
结论
2
与常规运动康复训练方案相比,渐进性活动与运动进阶训练方案更能促进患者膈肌功能、上下肢肌力和下肢运动功能的康复,提高生活质量。
Objective
2
To determine the effect of progressive and step-up mobilization and exercise training on functional rehabilitation in critically ill patients.
Methods
2
A total of 60 critically ill patients hospitalized in the Intensive Care Unit and High Dependence Unit of General Hospital of Southern Theater Command during September 1
2019 and September 1
2021 were prospectively recruited
and then randomly divided into observation group and control group
with 30 cases in each group. Both groups received routine treatment and nursing care. The patients of the control group received a conventional exercise rehabilitation training for 6 weeks
while those of the observation group underwent a 3-staged (passive
auxiliary
and active) progressive and step-up mobilization and exercise training for 6 weeks. Before and after the 6-week training
Fugl-Meyer Assessment of Lower Extremity (LE-FMA) was used to assess the motor function of the patient
and Modified Barthel Index (MBI) was used to assess their abilities for activities of daily living. Muscle function was assessed by Medical Research Council Scale (MRC) scale and bedside diaphragmatic ultrasonography before and at 2
4
and 6 weeks after training.
Results
2
After 2 weeks of training
the muscle strength and diaphragm excursion were decreased in both groups compared
and the decrease was more obvious in the control group (
P
<
0.05). After 4 and 6 weeks of training
the muscle strength and diaphragm excursion were improved in both groups (
P
<
0.05)
and the improvement was more significant in the observation group (
P
<
0.05). At the end of training
the scores of LE-FMA and MBI were improved in the 2 groups when compared with those before training (
P
<
0.05)
and the scores of the observation group were significantly higher than those of the control group (
P
<
0.05).
Conclusion
2
Compared with the conventional exercise rehabilitation training
our progressive and step-up mobilization and exercise training can more significantly promote patient's diaphragm function
upper and lower limb muscle strength and lower limb motor function
and thus improve the quality of life in critically ill patients.
ELY E W. The ABCDEF bundle: science and philosophy of how ICU liberation serves patients and families[J]. Crit Care Med, 2017, 45(2): 321-330. DOI: 10.1097/CCM.0000000000002175.
MALMGREN J, WALDENSTRÖM A C, RYLANDER C, et al . Long-term health-related quality of life and burden of disease after intensive care: development of a patient-reported outcome measure[J ] . Crit Care, 2021, 25(1): 82. DOI: 10.1186/s13054-021-03496-7.
HASHEM M D, PARKER A M, NEEDHAM D M. Early mobilization and rehabilitation of patients who are critically ill[J]. Chest, 2016, 150(3): 722-731. DOI: 10.1016/j.chest.2016.03.003.
SCHALLER S J, ANSTEY M, BLOBNER M, et al . Early, goal-directed mobilisation in the surgical intensive care unit: a randomised controlled trial[J ] . Lancet, 2016, 388(10052): 1377-1388. DOI: 10.1016/S0140-6736(16)31637-3.
赵贵美, 焦琳琳, 杨桂华. 早期循序渐进运动对ICU患者获得性衰弱影响的Meta分析[J]. 中华护理杂志, 2017, 52(2): 177-181. DOI: 10.3761/j.issn.0254-1769.2017.02.010.
ZHAO G M, JIAO L L, YANG G H. The effects of early progressive exercise on ICU acquired weakness: a meta-analysis[J]. Chin J Nurs, 2017, 52(2): 177-181. DOI: 10.3761/j.issn.0254-1769.2017.02.010.
贾金凤, 徐晓, 赵红梅. 早期渐进性运动训练对ICU老年病人自身肌力和自理能力的干预效果分析[J]. 实用老年医学, 2022, 36(4): 421-425. DOI: 10.3969/j.issn.1003-9198.2022.04.025.
JIA J F, XU X, ZHAO H M. Effect of early progressive exercise training on self muscle strength and self-care ability of elderly patients in ICU[J]. Pract Geriatr, 2022, 36(4): 421-425. DOI: 10.3969/j.issn.1003-9198.2022.04.025.
杜丽丽, 李晓茹, 赵彦杰. 分级化早期康复活动对ICU呼吸衰竭插管患者预后的影响[J]. 宁夏医学杂志, 2018, 40(11): 1010-1012. DOI: 10.13621/j.1001-5949.2018.11.1010.
DU L L, LI X R, ZHAO Y J. Effect of graded early rehabilitation activities on the prognosis of intubated patients with respiratory failure in the ICU[J]. Ningxia Med J, 2018, 40(11): 1010-1012. DOI: 10.13621/j.1001-5949.2018.11.1010.
HODGSON C L, STILLER K, NEEDHAM D M, et al . Expert consensus and recommendations on safety criteria for active mobilization of mechanically ventilated critically ill adults[J ] . Crit Care, 2014, 18(6): 658. DOI: 10.1186/s13054-014-0658-y.
倪莹莹, 王首红, 宋为群, 等. 神经重症康复中国专家共识(上)[J]. 中国康复医学杂志, 2018, 33(1): 7-14. DOI: 10.3969/j.issn.1001-1242.2018.01.003.
NI Y Y, WANG S H, SONG W Q, et al . Chinese expert consensus on rehabilitation of neurocritical patients (PART 1)[J ] . Chin J Rehabil Med, 2018, 33(1): 7-14. DOI: 10.3969/j.issn.1001-1242.2018.01.003.
MENDEZ-TELLEZ P A, NUSR R, FELDMAN D, et al . Early physical rehabilitation in the ICU: a review for the neurohospitalist[J ] . Neurohospitalist, 2012, 2(3): 96-105. DOI: 10.1177/1941874412447631.
潘世琴, 王丽, 王玉宇. 危重症患者肌力评定方法的研究进展[J]. 中国康复理论与实践, 2019, 25(9): 1052-1056. DOI: 10.3969/j.issn.1006?9771.2019.09.011.
PAN S Q, WANG L, WANG Y Y. Advance in muscle strength assessment for critical patients (review)[J]. Chin J Rehabilitation Theory Pract, 2019, 25(9): 1052-1056. DOI: 10.3969/j.issn.1006?9771.2019.09.011.
NETO SILVA I, DUARTE J A, PERRET A, et al . Diaphragm dysfunction and peripheral muscle wasting in septic shock patients: exploring their relationship over time using ultrasound technology (the MUSiShock protocol)[J ] . PLoS One, 2022, 17(3): e0266174. DOI: 10.1371/journal.pone.0266174.
张川林, 张泽菊, 米洁, 等. ICU活动量表的汉化及信效度研究[J]. 护理学杂志, 2019, 34(10): 46-48. DOI: 10.3870/j.issn.1001-4152.2019.10.046.
ZHANG C L, ZHANG Z J, MI J, et al . Translation of the ICU mobility scale into Chinese and validation[J ] . J Nurs Sci, 2019, 34(10): 46-48. DOI: 10.3870/j.issn.1001-4152.2019.10.046.
杨睿琦, 甘秀妮, 白雪, 等. ICU机械通气患者早期活动相关指南和共识的质量评价与内容分析[J]. 护理学杂志, 2021, 36(6): 5-10. DOI: 10.3870/j.issn.1001-4152.2021.06.005.
YANG R Q, GAN X N, BAI X, et al . Quality evaluation and content analysis of guidelines and consensus statements on early mobilization in mechanically ventilated patients in the ICU[J ] . J Nurs Sci, 2021, 36(6): 5-10. DOI: 10.3870/j.issn.1001-4152.2021.06.005.
李奎成, 唐丹, 刘晓艳, 等. 国内Barthel指数和改良Barthel指数应用的回顾性研究[J]. 中国康复医学杂志, 2009, 24(8): 737-740.
LI K C, TANG D, LIU X Y, et al . Review of the application of Barthel Index and Modified Barthel Index in China's mainland[J ] . Chin J Rehabil Med, 2009, 24(8): 737-740.
邢然然, 戴勇, 黄怀. 床旁超声在重症患者肺康复中的应用进展[J]. 中国康复理论与实践, 2021, 27(2): 187-190. DOI: 10.3969/j.issn.1006-9771.2020.00.010.
XING R R, DAI Y, HUANG H. Advance in point-of-care ultrasound for pulmonary rehabilitation in critically ill patients (review)[J]. Chin J Rehabil Theory Pract, 2021, 27(2): 187-190. DOI: 10.3969/j.issn.1006-9771.2020.00.010.
HERNÁNDEZ E D, FORERO S M, GALEANO C P, et al . Intra- and inter-rater reliability of Fugl-Meyer Assessment of Lower Extremity early after stroke[J ] . Braz J Phys Ther, 2021, 25(6): 709-718. DOI: 10.1016/j.bjpt.2020.12.002.
余佳丹, 喻鹏铭, 魏清川, 等. 重症康复研究进展[J]. 华西医学, 2018, 33(10): 1207-1212.
YU J D, YU P M, WEI Q C, et al . Study on critical illness rehabilitation[J ] . West China Med J, 2018, 33(10): 1207-1212.
FAN E, CHEEK F, CHLAN L, et al . An official American Thoracic Society Clinical Practice guideline: the diagnosis of intensive care unit-acquired weakness in adults[J ] . Am J Respir Crit Care Med, 2014, 190(12): 1437-1446. DOI: 10.1164/rccm.201411-2011ST.
BERG H E, LARSSON L, TESCH P A. Lower limb skeletal muscle function after 6 wk of bed rest[J]. J Appl Physiol (1985), 1997, 82(1): 182-188. DOI: 10.1152/jappl.1997.82.1.182.
MAYER K P, THOMPSON BASTIN M L, MONTGOMERY-YATES A A, et al . Acute skeletal muscle wasting and dysfunction predict physical disability at hospital discharge in patients with critical illnes s[J ] . Crit Care, 2020, 24(1): 637. DOI: 10.1186/s13054-020-03355-x.
VANHOREBEEK I, LATRONICO N, VAN DEN BERGHE G. ICU-acquired weakness[J]. Intensive Care Med, 2020, 46(4): 637-653. DOI: 10.1007/s00134-020-05944-4.
DRES M, DUBÉ B P, MAYAUX J, et al . Coexistence and impact of limb muscle and diaphragm weakness at time of liberation from mechanical ventilation in medical intensive care unit patients[J ] . Am J Respir Crit Care Med, 2017, 195(1): 57-66. DOI: 10.1164/rccm.201602-0367OC.
LIU K, OGURA T, TAKAHASHI K, et al . A progressive early mobilization program is significantly associated with clinical and economic improvement: a single-center quality comparison study[J ] . Crit Care Med, 2019, 47(9): e744-e752. DOI: 10.1097/CCM.0000000000003850.
SWASH M, DE CARVALHO M. Intensive care unit-acquired weakness: neuropathology[J]. J Clin Neurophysiol, 2020, 37(3): 197-199. DOI: 10.1097/WNP.0000000000000660.
KNIGHT J, NIGAM Y, JONES A. Effects of bedrest 1: cardiovascular, respiratory and haematological systems[J]. Nurs Times, 2009, 105(21): 16-20.
KNIGHT J, NIGAM Y, JONES A. Effects of bedrest 2: gastrointestinal, endocrine, renal, reproductive and nervous systems[J]. Nurs Times, 2009, 105(22): 24-27.
NIGAM Y, KNIGHT J, JONES A. Effects of bedrest 3: musculoskeletal and immune systems, skin and self-perception[J]. Nurs Times, 2009, 105(23): 18-22.
曲斯伟, 杨晓龙, 孙丽, 等. 早期康复训练对机械通气重症脑卒中患者的影响[J]. 中国康复医学杂志, 2020, 35(11): 1302-1308. DOI: 10.3969/j.issn.1001-1242.2020.11.005.
QU S W, YANG X L, SUN L, et al . Effects of early mobilisation and rehabilitation on mechanically ventilated critically ill patients with stroke[J ] . Chin J Rehabil Med, 2020, 35(11): 1302-1308. DOI: 10.3969/j.issn.1001-1242.2020.11.005.
ZHANG L, HU W S, CAI Z Y, et al . Early mobilization of critically ill patients in the intensive care unit: a systematic review and meta-analysis[J ] . PLoS One, 2019, 14(10): e0223185. DOI: 10.1371/journal.pone.0223185.
王玉梅, 黄海燕, 熊莉娟, 等. ICU患者早期活动有效性及安全性影响的系统评价再评价[J]. 解放军护理杂志, 2019, 36(1): 16-20. DOI: 10.3969/j.issn.1008-9993.2019.01.00.
WANG Y M, HUANG H Y, XIONG L J, et al . Effectiveness and safety of early mobilization in ICU: an overview of systematic reviews[J ] . Nurs J Chin PLA, 2019, 36(1): 16-20. DOI: 10.3969/j.issn.1008-9993.2019.01.00.
武亮, 郭琪, 胡菱, 等. 中国呼吸重症康复治疗技术专家共识[J]. 中国老年保健医学, 2018, 16(5): 3-11.
WU L, GUO Q, HU L, et al . Expert consensus on rehabilitation technology of respiratory intensive care patients in China[J ] . Chin J Geriatr Care, 2018, 16(5): 3-11.
王秋雁, 边仁秀, 戎军, 等. 浙江省重症康复专家共识[J]. 浙江医学, 2017, 39(24): 2191-2196, 2209.
WANG Q Y, BIAN R X, RONG J, et al . Expert consensus on intensive care rehabilitation in Zhejiang Province[J ] . Zhejiang Med J, 2017, 39(24): 2191-2196, 2209.
姚丽, 尹瑞元, 杨丽平, 等. 医务人员对ICU早期康复认知、态度及临床实践的现状调查[J]. 中国护理管理, 2020, 20(10): 1475-1481. DOI: 10.3969/j.issn.1672-1756.2020.10.010.
YAO L, YIN R Y, YANG L P, et al . Cognition, attitudes and clinical practice on early rehabilitation among ICU patients[J ] . Chin Nurs Manag, 2020, 20(10): 1475-1481. DOI: 10.3969/j.issn.1672-1756.2020.10.010.
吕露露, 张雪静. 三级医院ICU重症患者早期活动现状及障碍因素调查[J]. 护理学杂志, 2020, 35(10): 31-34. DOI: 10.3870/j.issn.1001-4152.2020.10.031.
LYU L L, ZHANG X J. Early mobilization of critically ill patients in the ICU of tertiary hospitals and its barriers[J]. J Nurs Sci, 2020, 35(10): 31-34. DOI: 10.3870/j.issn.1001-4152.2020.10.031.
MORRIS P E, GOAD A, THOMPSON C, et al . Early intensive care unit mobility therapy in the treatment of acute respiratory failure[J ] . Crit Care Med, 2008, 36(8): 2238-2243. DOI: 10.1097/CCM.0b013e318180b90e.
SCHUJMANN D S, TEIXEIRA GOMES T, LUNARDI A C, et al . Impact of a progressive mobility program on the functional status, respiratory, and muscular systems of ICU patients: a randomized and controlled trial[J ] . Crit Care Med, 2020, 48(4): 491-497. DOI: 10.1097/CCM.0000000000004181.
GOSSELINK R, CLERCKX B, ROBBEETS C, et al . Physiotherapy in the intensive care unit[J ] . Neth J Crit Care, 2011, 15(2): 1-10.
0
Views
0
下载量
0
CSCD
Publicity Resources
Related Articles
Related Author
Related Institution
京公网安备11010802024621
