400038 重庆,陆军军医大学(第三军医大学)第一附属医院关节外科
Received:14 December 2021,
Revised:2022-03-29,
Published:15 August 2022
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Fuyou WANG, Puquan WANG. Application and development of 3D printing technology in bone and joint surgery[J]. Journal of Army Medical University, 2022, 44(15): 1508-1515.
Fuyou WANG, Puquan WANG. Application and development of 3D printing technology in bone and joint surgery[J]. Journal of Army Medical University, 2022, 44(15): 1508-1515. DOI: 10.16016/j.2097-0927.202112120.
个性化精准医疗是现代临床医学的核心追求,3D打印技术以CT、MRI等影像数据为基础,以逐层叠加打印为手段,实现与患处的个性化匹配和精准治疗,开创了医工协作攻关的新纪元。本文从仿生打印模型、个性化金属植入物和生物打印3个方面阐述3D打印技术在骨关节外科领域的典型应用,阐明骨关节仿生模型在手术教学、实践和可视化医患沟通中的显著效果,但影像分辨率和打印精度尚待提高;分析金属植入物尤其是3D打印多孔钽在大段骨缺损治疗中的安全性和有效性,以及生物打印骨与软骨的诸多尝试和生物墨水与细胞存活等方面的挑战。3D打印技术促进了骨关节外科诊疗水平的提高,未来将持续研发仿生超精细模型,深入研究钽金属微观结构特性对生物学功能的影响,制备高品质钽植入物,同时探索骨组织工程打印技术的突破方向。
Personalized precision medicine is the core pursuit of modern clinical medicine. Based on CT
MRI
and other image data
3D printing technology achieves personalized matching and precise treatment with the affected area through layer-by-layer superposition printing and promotes new cooperation between medicine and industry. This paper expounds on the typical application of 3D printing technology in the field of bone and joint surgery from 3 aspects: bionic printing model
metallic implants
and bioprinting. The remarkable effects of a bone joint bionic model are further clarified in surgical teaching
practice
and visual doctor-patient communication
but the image resolution and printing accuracy need to be further improved. We analyze the safety and effectiveness of metal implants
especially 3D printed porous tantalum
in the treatment of large bone defects
and many attempts of bioprinting bone and cartilage
as well as the challenges of biological ink and cell survival. 3D printing technology has promoted the improvement of the diagnosis and treatment of bone and joint surgery. In the future
researches should further study the effect of tantalum microstructure on biological function
prepare high-quality tantalum implants
and explore the breakthrough direction of bone tissue engineering printing technology.
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