Epidemiological study of dry eye disease and its influencing factors among soldiers on an island in South China Sea

Chenyue LI; Peng HUANG; Zeyu TAN; Weifeng TAN; Yang LIU; Hao WANG

doi:10.16016/j.1000-5404.202106086

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Epidemiological study of dry eye disease and its influencing factors among soldiers on an island in South China Sea

Military Medicine | 更新时间：2026-01-09

- Epidemiological study of dry eye disease and its influencing factors among soldiers on an island in South China Sea
- Journal of Third Military Medical University Vol. 43, Issue 24, Pages: 2603-2608(2021)
- 作者机构：
  
  573100 海南三沙，南部战区海军91892部队医院
- 作者简介：
- 基金信息：
- DOI：10.16016/j.1000-5404.202106086
  CLC： R777.34;R821.2;824
- Received：13 June 2021，
  
  Revised：2021-07-13，
  
  Published：30 December 2021
- 稿件说明：
移动端阅览
Chenyue LI, Peng HUANG, Zeyu TAN, et al. Epidemiological study of dry eye disease and its influencing factors among soldiers on an island in South China Sea[J]. Journal of Third Military Medical University, 2021, 43(24): 2603-2608.
DOI：

Chenyue LI, Peng HUANG, Zeyu TAN, et al. Epidemiological study of dry eye disease and its influencing factors among soldiers on an island in South China Sea[J]. Journal of Third Military Medical University, 2021, 43(24): 2603-2608. DOI： 10.16016/j.1000-5404.202106086.

摘要

目的

掌握现阶段南海某驻岛部队官兵在特殊环境下干眼症的流行病学特点并分析其发病影响因素。

方法

2021年1月1日至3月31日对南海某驻岛部队官兵做随机抽样调查，研究对象填写Salisbury眼睛评价问卷调查表(Salisbury Eye Evaluation Questionnaire

SEEQ)并接受眼科常规检查、泪膜破裂时间测定(tear film break-up time

BUT)试验、泪液分泌功能测定(schirmer I test，SIT)试验、角膜荧光素钠染色(fluorescein stain test，FLT)试验，根据干眼症诊断确定官兵干眼症患病率。通过单因素和多因素Logistic分析干眼症患病的影响因素。

结果

在随机抽样的612名研究对象中，545名规范有效地完成了干眼症问卷调查表、眼科检查以及各项试验，有效参与率为89.05%。问卷调查显示，每个症状的出现频率与其持续时间均呈负相关，其中有100名(18.35%)表现为频繁甚至持续出现眼干涩症状，部分研究对象可同时表现为多种症状。在BUT试验中，有415只眼(38.08%)

10 s；SIT试验中，有416只眼(38.16%)

10 mm/min；FLT试验中，有174只眼(15.96%)

0分。根据干眼症诊断标准，共175名(32.11%)被确诊患有干眼症，通过干眼症危险因素的单因素和多因素Logistic回归分析

显示，驻岛时间

3年(

=0.018)、工作环境高热(

0.001)、日晒(

=0.048)、长期注视电子屏幕(

=0.004)和吸烟史(

=0.033)等因素差异有统计学意义。

结论

南海某驻岛部队官兵干眼症患病率高。驻岛时间>3年、工作环境高热、日晒、长期注视电子屏幕和吸烟史为干眼症危险因素。

Abstract

Objective

To investigate the epidemiological characteristics of dry eye disease in soldiers located on an island in South China Sea and to analyze its influencing factors.

Methods

From January 1 to March 31

2021

a random sample survey was conducted on the soldiers and officers of a military unit located on the island. The subjects were required to fill Salisbury Eye Evaluation Questionnaire (SEEQ)

and subsequently given routine ophthalmological examination as well as tear film break-up time test (BUT)

Schirmer Ⅰ test (SIT) and fluorescein stain test (FLT)

so as to calculate the prevalence of dry eye among the subjects. Univariate and multivariate logistic regression models were performed to identify the influencing factors for dry eye.

Results

Among the 612 sampled subjects

545 participants completed the questionnaire and underwent ophthalmological examination and other tests effectively

with a survey response rate of 89.05%. The questionnaire indicated that the frequency of each symptom was negatively correlated with its duration. One hundred subjects (18.35%) showed frequently and even persistent dryness of eyes

and some presented multiple dry eye symptoms simultaneously. In the BUT test

415 eyes (38.08%) were

10 s; In the SIT test

416 eyes (38.16%) showed

10 mm/min; In the FLT test

174 eyes (15.96%) scored

0. According to the diagnosis standard of dry eye disease

175 subjects (32.11%) were consequently identified as dry eye. Univariate and multivariate logistic regression analyses indicated that station duration on an island

3 years (

=0.018)

high temperature during working (

0.001)

sun exposure (

=0.048)

longtime staring at digital screens (

=0.004) and smoking history (

=0.033) were of statistical significances.

Conclusion

The prevalence of dry eye is quit high among the soldiers stationing on the island in South China Sea. Station time on an island longer than 3 years

high temperature during working

sun exposure

overuse of digital screens and smoking history are the risk factors for dry eye disease.

关键词

Keywords

references

HAN S B, LIU Y C, MOHAMED-NORIEGA K, et al . Objective imaging diagnostics for dry eye disease[J ] . J Ophthalmol, 2020, 2020: 3509064. DOI: 10.1155/2020/3509064.

TSUBOTA K, PFLUGFELDER S C, LIU Z G, et al . Defining dry eye from a clinical perspective[J ] . Int J Mol Sci, 2020, 21(23): E9271. DOI: 10.3390/ijms21239271.

廖国栋, 吴国华. 西沙气候特点及电子产品曝露试验价值[C]. 中国电子学会电子产品防护技术'98研讨会, 1998.

LIAO G D, WU G H. The climatic characteristics of Xisha and the value of exposure test of electronic products[C]. Symposium on Protection Technology of Electronic Products'98, Chinese Institute of Electronics, 1998.

亚洲干眼协会中国分会, 海峡两岸医药卫生交流协会眼科学专业委员会眼表与泪液病学组, 中国医师协会眼科医师分会眼表与干眼学组. 中国干眼专家共识: 定义和分类(2020年)[J]. 中华眼科杂志, 2020, 6(6): 418-422. DOI: 10.3760/cma.j.cn112142-20200316-00190.

China Branch of Asian Dry Eye Association, Ophthalmic Surface and Tear Epidemiology Group of Ophthalmology Professional Committee of Cross-Strait Medical and Health Exchange Association, Ophthalmology and Dry Eye Group of Ophthalmologist Branch of Chinese Medical Doctor Association. China dry eye expert consensus: definition and classification (2020)[J]. Chin J Ophthalmol, 2020, 6(6): 418-422. DOI: 10.3760/cma.j.cn112142-20200316-00190.

刘祖国, 彭娟. 干眼的诊断与治疗规范[J]. 眼科研究, 2008, 26(3): 161-164.

LIU Z G, PENG J. Guidelines for the diagnosis and treatment of dry eyes[J]. Ophthalmol Res, 2008, 26(3): 161-164.

PARK J, CHOI Y, HAN G, et al . Evaluation of tear osmolarity measured by I-Pen osmolarity system in patients with dry eye[J ] . Sci Rep, 2021, 11(1): 7726. DOI: 10.1038/s41598-021-87336-2.

YOON C H, RYU J S, MOON J, et al . Association between aging-dependent gutmicrobiome dysbiosis and dry eye severity in C57BL/6 male mouse model: a pilot study[J ] . BMC Microbiol, 2021, 21(1): 106. DOI: 10.1186/s12866-021-02173-7.

DIANA M P, ANA B. Tear evaluation by anterior segment OCT in dry eye disease[J]. Rom J Ophthalmol, 2021, 65(1): 25-30. DOI: 10.22336/rjo.2021.6.

胡益女. 三种常用干眼问卷调查表的比较研究[D]. 温州: 温州医科大学, 2011.

HU Y N. A comparative study of three common dry eye questionnaire[D]. Wenzhou: Wenzhou Medical University, 2011.

BREWITT H, SISTANI F. Dry eye disease: the scale of the problem[J]. Surv Ophthalmol, 2001, 45(Suppl 2): S199-S202. DOI: 10.1016/s0039-6257(00)00202-2.

JIE Y, XU L, WU Y Y, et al . Prevalence of dry eye among adult Chinese in the Beijing Eye Study[J ] . Eye (Lond), 2009, 23(3): 688-693. DOI: 10.1038/sj.eye.6703101.

LU P, CHEN X M, LIU X Y, et al . Dry eye syndrome in elderly Tibetans at high altitude: a population-based study in China[J ] . Cornea, 2008, 27(5): 545-551. DOI: 10.1097/ICO.0b013e318165b1b7.

DE PAIVA C S. Effects of aging in dry eye[J]. Int Ophthalmol Clin, 2017, 57(2): 47-64. DOI: 10.1097/ⅡO.0000000000000170.

TRUONG S, COLE N, STAPLETON F, et al . Sex hormones and the dry eye[J ] . Clin Exp Optom, 2014, 97(4): 324-336. DOI: 10.1111/cxo.12147.

MCCULLEY J P, ARONOWICZ J D, UCHIYAMA E, et al . Correlations in a change in aqueous tear evaporation with a change in relative humidity and the impact[J ] . Am J Ophthalmol, 2006, 141(4): 758-760. DOI: 10.1016/j.ajo.2005.10.057.

HUANG A, JANECKI J, GALOR A, et al . Association of the indoor environment with dry eye metrics[J ] . JAMA Ophthalmol, 2020, 138(8): 867-874. DOI: 10.1001/jamaophthalmol.2020.2237.

NAGYMIHÁLYI A, DIKSTEIN S, TIFFANY J M. The influence of eyelid temperature on the delivery of meibomian oil[J]. Exp Eye Res, 2004, 78(3): 367-370.DOI: 10.1016/s0014-4835(03)00197-0.

BORCHMAN D, FOULKS G N, YAPPERT M C, et al . Factors affecting evaporation rates of tear film components measured in vitro[J ] . Eye Contact Lens, 2009, 35(1): 32-37. DOI: 10.1097/ICL.0b013e318193f4fc.

MCKAY T B, KARAMICHOS D. Quercetin and the ocular surface: What we know and where we are going[J]. Exp Biol Med (Maywood), 2017, 242(6): 565-572. DOI: 10.1177/1535370216685187.

CALONGE M, PINTO-FRAGA J, GONZÁLEZ-GARCÍA M J, et al . Effects of the external environment on dry eyedisease[J ] . Int Ophthalmol Clin, 2017, 57(2): 23-40. DOI: 10.1097/ⅡO.0000000000000168.

CHAWLA A, LIM T C, SHIKHARE S N, et al . Computer vision syndr ome: darkness under the shadow of light[J ] . J L'association Can Des Radiol, 2019, 70(1): 5-9. DOI: 10.1016/j.carj.2018.10.005.

MAREK V, MÉLIK-PARSADANIANTZ S, VILLETTE T, et al . Blue light phototoxicity toward human corneal and conjunctival epithelial cells in basal and hyperosmolarconditions[J ] . Free Radic Biol Med, 2018, 126: 27-40. DOI: 10.1016/j.freeradbiomed.2018.07.012.

SHAH S, JANI H. Prevalence and associated factors of dryeye: Our experience in patients above 40 years of age at a Tertiary CareCenter[J]. Oman J Ophthalmol, 2015, 8(3): 151-156. DOI: 10.4103/0974-620X.169910.

GRZYBOWSKI A, NITA M. Smoking and eye pathologies. A systemic review. part I. anterior eye segment pathologies[J]. Curr Pharm Des, 2017, 23(4): 629-638. DOI: 10.2174/1381612822666161129152041.

YOON K C, SONG B Y, SEO M S. Effects of smoking on tear film and ocularsurface[J]. Korean J Ophthalmol, 2005, 19(1): 18-22. DOI: 10.3341/kjo.2005.19.1.18.

THOMAS J, JACOB G P, ABRAHAM L, et al . The effect of smoking on the ocular surface and the precorneal tear film[J ] . Australas Med J, 2012, 5(4): 221-226. DOI: 10.4066/AMJ.2012.1035.

LI J, ZHANG G W, NIAN S, et al . Dry eye induced by exposure to cigarette smoke pollution: an in vivo and in vitrostudy[J ] . Free Radic Biol Med, 2020, 153: 187-201. DOI: 10.1016/j.freeradbiomed.2020.04.007.

JONES L, DOWNIE L E, KORB D, et al . TFOS DEWS Ⅱ management and therapy report[J ] . Ocul Surf, 2017, 15(3): 575-628. DOI: 10.1016/j.jtos.2017.05.006.

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