Prevalence and influencing factors of chronic obstructive pulmonary disease in rural areas of Moyu County, Xinjiang

Yide WANG; Zheng LI; Dan XU; Jing JING; Chunyan LIAO; Ting WANG; Siming TAO; Jing JIN; Fengsen LI

doi:10.16016/j.1000-5404.202105079

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Prevalence and influencing factors of chronic obstructive pulmonary disease in rural areas of Moyu County, Xinjiang

Public Health and Preventive Medicine | 更新时间：2026-01-09

- Prevalence and influencing factors of chronic obstructive pulmonary disease in rural areas of Moyu County, Xinjiang
- Journal of Third Military Medical University Vol. 43, Issue 22, Pages: 2485-2494(2021)
- 作者机构：
  
  830000 乌鲁木齐，新疆医科大学第四临床医学院
- 作者简介：
- 基金信息：
  
  the Key Special Subproject of Precision Medicine Research From National Key R & D Program of China(2017YFC0907203)
- DOI：10.16016/j.1000-5404.202105079
  CLC： R195.4;R563.9
- Received：16 May 2021，
  
  Revised：2021-08-08，
  
  Published：30 November 2021
- 稿件说明：
移动端阅览
Yide WANG, Zheng LI, Dan XU, et al. Prevalence and influencing factors of chronic obstructive pulmonary disease in rural areas of Moyu County, Xinjiang[J]. Journal of Third Military Medical University, 2021, 43(22): 2485-2494.
DOI：

Yide WANG, Zheng LI, Dan XU, et al. Prevalence and influencing factors of chronic obstructive pulmonary disease in rural areas of Moyu County, Xinjiang[J]. Journal of Third Military Medical University, 2021, 43(22): 2485-2494. DOI： 10.16016/j.1000-5404.202105079.

摘要

目的

分析中国新疆维吾尔自治区和田地区墨玉县乡村地区慢性阻塞性肺疾病（chronic obstructive pulmonary disease

COPD）现况及影响因素，为当地该病的早期预防和选择干预策略提供科学依据。

方法

选择中国西北区域自然人群队列研究中新疆乡村地区的基线调查人群为研究对象。2018年6-12月在维吾尔自治区和田地区墨玉县乡村地区对35岁及以上自然人群进行现场调查，完成受试者调查问卷、体格检查和肺功能测量等数据的收集，最终获得有效样本3 249份。采用Stata 13.0软件进行χ

检验、趋势χ

检验，采用单因素及多因素二分类Logistic回归分析相关调查因素与COPD患病的关系。

结果

当地共有394例（12.13%）受试者被诊断为COPD。40岁以上调查人群COPD患病率为12.59%（95%

：11.45%~13.83%），并且随年龄增长而增加（趋势χ

=71.990；

0.001）。其中40岁以上人群中男性患病率（15.3%）显著高于女性（10.1%），差异具有统计学意义（χ

=14.216；

0.001）。在控制混杂因素后，多因素Logistic回归分析结果显示：高龄（50~＜60岁：

=1.800，95%

：1.203~2.694；60~＜70岁：

=3.035，95%

：1.986~4.637；≥70岁：

=5.602，95%

：2.419~12.973）、主动吸烟（

=1.422，95%

：1.077~1.877）、使用传统生物燃料或煤（

=2.258，95%

：1.022~4.991）、有肺结核病史（

=2.181，95%

：1.291~3.682）是当地COPD患病的危险因素。较高水平BMI（24.0~＜28.0：

=0.611，95%

：0.449~0.830；≥28.0：

=0.470，95%

：0.258~0.858）和使用通风装置（

=0.666，95%

：0.473~0.937）的人群患COPD的风险较低。

结论

中国新疆墨玉县乡村地区COPD患病率为12.13%，与国内报道数据基本一致。除高龄、吸烟以外，使用煤或传统生物质作燃料、缺少通风装置以及有肺结核病史与当地COPD患病风险密切相关。

Abstract

Objective

To analyze the status and influencing factors of chronic obstructive pulmonary disease (COPD) in rural areas of Moyu County

in the southern part of Xinjiang

and to provide scientific basis for early prevention and intervention strategies.

Methods

The baseline survey population in rural Xinjiang of the Natural Population Cohort Study in Northwest China was selected as the research object. A field survey was conducted from June to December 2018 in the rural areas of Moyu County

among the natural population aged 35 to 74

and the results of a questionnaire

physical examination and lung function measurement were collected. Finally

3 249 valid samples were obtained. Stata 13.0 software was used for

Chi

-square test and trend

Chi

-square test. Univariate and multivariate binary logistic regression were adopted to analyze the correlation between related investigation factors and COPD.

Results

A total of 394 subjects (12.13%) were diagnosed with COPD. The prevalence of COPD was 12.59% (95%

: 11.45%~13.83%) in subjects over 40 years old

it was increased with age (

Chi

-square trend=71.990

0.001)

and that of men was significantly higher than that of women (15.3% vs 10.1%

Chi

-square=14.216

0.001). After controlling confounding factors

multivariate logistic regression analysis showed that advanced age (50~

60 years old:

=1.800

95%

: 1.203~2.694; 60~

70 years old:

=3.035

95%

: 1.986~4.637; ≥70 years old:

=5.602

95%

: 2.419~12.973)

active smoking (

=1.422

95%

: 1.077~1.877)

use of traditional biofuels or coal (

=2.258

95%

: 1.022~4.991)

and a history of tuberculosis (

=2.181

95%

: 1.291~3.682) were independent risk factors for local COPD. People with higher BMI (24.0~

28.0:

=0.611

95%

: 0.449~0.830; ≥28.0:

=0.470

95%

: 0.258~0.858) and using ventilation devices (

=0.666

95%

: 0.473~0.937) had a lower risk of COPD.

Conclusion

The prevalence of COPD in rural areas of Moyu County is 12.13%

basically consistent with the domestic reports. In addition to the common risk factors like advanced age and smoking

the use of traditional biofuels or coal

lack of ventilation

and a history of tuberculosis are also closely associated with the risk of local COPD.

关键词

Keywords

references

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