Error analysis of 4-dimensional computed tomography image reconstruction in uniform motion state

Hongya DAI; Yibing ZHOU; Jindong QIAN; Dingqiang YANG; Xiaojing WEN; Wencai PAN; Jianguo SUN

doi:10.16016/j.1000-5404.202104025

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Error analysis of 4-dimensional computed tomography image reconstruction in uniform motion state

Clinical Medicine | 更新时间：2026-01-09

- Error analysis of 4-dimensional computed tomography image reconstruction in uniform motion state
- Journal of Third Military Medical University Vol. 43, Issue 19, Pages: 1913-1918(2021)
- 作者机构：
  
  1.400037 重庆，陆军军医大学(第三军医大学)第二附属医院: 肿瘤科
  2.400037 重庆，陆军军医大学(第三军医大学)第二附属医院: 设备科
- 作者简介：
- 基金信息：
  
  the General Project of Joint Medical Research of Chongqing Science and Technology Commission and Public Health Commission(2021MSXM154);the National Key R & D Program of China(2016YFC0103100)
- DOI：10.16016/j.1000-5404.202104025
  CLC： R319;R332.1;R814.42
- Received：06 April 2021，
  
  Revised：2021-06-10，
  
  Published：15 October 2021
- 稿件说明：
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Hongya DAI, Yibing ZHOU, Jindong QIAN, et al. Error analysis of 4-dimensional computed tomography image reconstruction in uniform motion state[J]. Journal of Third Military Medical University, 2021, 43(19): 1913-1918.
DOI：

Hongya DAI, Yibing ZHOU, Jindong QIAN, et al. Error analysis of 4-dimensional computed tomography image reconstruction in uniform motion state[J]. Journal of Third Military Medical University, 2021, 43(19): 1913-1918. DOI： 10.16016/j.1000-5404.202104025.

摘要

目的

利用呼吸运动体模研究均匀运动状态的四维CT(four-dimensional computed tomography，4DCT)图像重建的准确性。

方法

采用呼吸运动体模模拟肺部肿瘤在头脚方向做余弦波运动，根据呼吸运动幅度(A)和周期(T)分为6组(A=0.5 cm，T=6 s；A=0.5 cm，T=3 s；A=1.0 cm，T=6 s；A=1.0 cm，T=3 s；A=1.5 cm，T=6 s；A=1.5 cm，T=3 s)。采用Philips大孔径CT模拟机进行4DCT扫描。6组运动采用相同的扫描参数分别采集2次。在重建的4DCT图像上勾画内靶区(internal target volume，ITV)，统计ITV的体积和长度，并与理论值比较，分析4DCT重建误差。

结果

ITV在6组4DCT重建图像上均有误差，TIV体积误差相对值范围为1.13%~27.64%；ITV长度误差范围为-0.95~0.03 cm，ITV长度平均误差为0.25 cm。在A=1.5 cm，T=6 s时，ITV重建误差最大，前后2次扫描的体积误差分别为27.64%和19.04%，长度误差分别为0.11 cm和0.84 cm。呼吸运动参数和扫描参数完全一致的前后2次4DCT图像重建的靶体积和长度也均存在差异，在A=0.5 cm，T=6 s时，前后2次的ITV体积误差分别为14.47%和4.43%，相差达10.00%。

结论

均匀运动情况下4DCT图像重建存在误差，且误差大小随机化，具有不可预见性。

Abstract

Objective

To investigate the accuracy of 4-dimensional computed tomography (4DCT) image reconstruction in uniform motion state using respiratory motion phantom.

Methods

The cosine wave movements of lung tumor in the craniocaudal direction were simulated on a respiratory motion phantom

and the simulations were divided into 6 groups according to the respiratory motion amplitude (A) and the breathing period (T)

that is

A=0.5 cm

T=6 s; A=0.5 cm

T=3 s; A=1.0 cm

T=6 s; A=1.0 cm

T=3 s; A=1.5 cm

T=6 s; A=1.5 cm T=3 s. 4DCT scans were acquired using Philips big bore CT simulator

and the movements were scanned twice for each group

with same scanning parameters. Finally

the internal target volume (ITV) was delineated on the reconstructed 4DCT images

and the volume and length of ITVs were measured and compared with their theoretical values to analyze reconstruction errors of 4DCT.

Results

There were errors in all the 6 groups of ITV delineated on the reconstructed 4DCT images. The relative error range of ITV volume was from 1.13% to 27.64%

and that of ITV length was from -0.95~0.03 cm. The average ITV length error was 0.25 cm. When A=1.5 cm and T=6 s

the reconstruction error showed the maximum

and the volume errors presented 27.64% and 19.04%

while the length errors were 0.11 and 0.84 cm between the 2 scans. There were also differences between the results of 2 scans under the same respiratory motion parameters and scanning parameters. When A=0.5 cm and T=6 s

the volume errors of ITV were 14.47% and 4.43% in the 2 scans

with a difference of 10.00%.

Conclusion

There remain errors in 4DCT image reconstruction under uniform motion

and the size of the error is randomized and unpredictable.

关键词

Keywords

references

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