Differences in CT findings between solid solitary mucinous lung invasive adenocarcinoma and non-mucinous lung invasive adenocarcinoma

Shun WU; Qi LI; Xiaoqun HE; Junwei GONG; Jiwen HUO

doi:10.16016/j.1000-5404.202104020

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Differences in CT findings between solid solitary mucinous lung invasive adenocarcinoma and non-mucinous lung invasive adenocarcinoma

Clinical Medicine | 更新时间：2026-01-09

- Differences in CT findings between solid solitary mucinous lung invasive adenocarcinoma and non-mucinous lung invasive adenocarcinoma
- Journal of Third Military Medical University Vol. 43, Issue 19, Pages: 1919-1924(2021)
- 作者机构：
  
  400016 重庆，重庆医科大学附属第一医院放射科
- 作者简介：
- 基金信息：
- DOI：10.16016/j.1000-5404.202104020
  CLC： R730.261;R734.2;R814.42
- Received：05 April 2021，
  
  Revised：2021-06-06，
  
  Published：15 October 2021
- 稿件说明：
移动端阅览
Shun WU, Qi LI, Xiaoqun HE, et al. Differences in CT findings between solid solitary mucinous lung invasive adenocarcinoma and non-mucinous lung invasive adenocarcinoma[J]. Journal of Third Military Medical University, 2021, 43(19): 1919-1924.
DOI：

Shun WU, Qi LI, Xiaoqun HE, et al. Differences in CT findings between solid solitary mucinous lung invasive adenocarcinoma and non-mucinous lung invasive adenocarcinoma[J]. Journal of Third Military Medical University, 2021, 43(19): 1919-1924. DOI： 10.16016/j.1000-5404.202104020.

摘要

目的

探讨实性孤立性肺浸润性黏液腺癌(solid solitary mucinous lung invasive adenocarcinoma

SS-MLIA)与实性孤立性肺浸润性非黏液腺癌(solid solitary non-mucinous lung invasive adenocarcinoma

SS-NMLIA)的CT表现差异。

方法

回顾性分析本院2014-2020年经手术病理证实的47例SS-MLIA(黏液腺癌组)与277例SS-NMLIA(对照组)患者的临床及CT资料，比较两组临床特征及CT征象。

结果

① 临床特征: 两组间性别、年龄、吸烟史及临床TNM分期差异均无统计学意义。②平扫CT征象: 黏液腺癌组下叶分布、充气支气管征、钙化及紧贴胸膜的出现率均显著高于对照组，而胸膜牵拉征出现率显著低于对照组(

均

0.05)，而两组边界情况、分叶征、毛刺征及含气腔隙的出现率差异均无统计学意义。③增强CT征象: 黏液腺癌组血管造影征及液性无强化低密度区的出现率均显著高于对照组，而△CT

动脉期

及△CT

静脉期

均显著低于对照组(

均＜0.05)。

结论

SS-MLIA与SS-NMLIA的CT表现存在一定差异，下叶分布、充气支气管征、钙化、紧贴胸膜、强化程度较轻、血管造影征及液性无强化低密度区需高度警惕SS-MLIA。

Abstract

Objective

To investigate the differential CT features between solid solitary mucinous lung invasive adenocarcinoma (SS-MLIA) and solid solitary non-mucinous lung invasive adenocarcinoma (SS-NMLIA).

Methods

A total of 47 patients with SS-MLIA and 277 patients with SS-NMLIA confirmed by pathology after operation in our hospital from January 2014 to December 2020 were included in this study. Their CT features and findings were retrospectively analyzed and compared between the 2 groups.

Results

① Clinical features: there were no significant differences in gender

age

smoking history

and clinical TNM stage between the 2 groups. ② Plain CT findings: The incidences of distribution in the lower lobe of the lung

air bronchogram

calcification

and pleural attachment were more frequently seen in SS-MLIA

whereas pleural retraction was more common in SS-NMLIA (all

0.05). However

no significant differences were observed in the boundary of tumors

lobulation

spiculation and air space between both groups. ③ Contrast-enhanced CT findings: CT angiogram and unenhanced low-density area were more common in SS-MLIA

and the △CT values of SS-MLIA in both arterial and venous phase were much lower than those of SS-NMLIA (all

0.05).

Conclusion

SS-MLIA and SS-NMLIA have different CT features. Distribution in the lower lobe of the lung

air bronchogram

calcification

pleural attachment

CT angiogram

unenhanced low-density area

and slightly enhancement raise suspicion for SS-MLIA.

关键词

Keywords

references

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