Correlation analysis of basic vital signs and behavioral score of disorders of consciousness in patients with brainstem hemorrhage

Shiyi ZUO; Juan SUN; Zhenzhen CHEN; Hanxu CAI; Zhi HU; Zhongxiang YAO; Yong LIU

doi:10.16016/j.1000-5404.202102092

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Correlation analysis of basic vital signs and behavioral score of disorders of consciousness in patients with brainstem hemorrhage

Monographic Reports : Basic and clinical studies for disorders of consciousness | 更新时间：2026-01-09

- Correlation analysis of basic vital signs and behavioral score of disorders of consciousness in patients with brainstem hemorrhage
- Journal of Third Military Medical University Vol. 43, Issue 15, Pages: 1418-1423(2021)
- 作者机构：
  
  1.400037 重庆，陆军军医大学(第三军医大学)第二附属医院疼痛与康复医学科
  2.400038 重庆，陆军军医大学(第三军医大学)基础医学院生理学教研室，脑与智能研究院
- 作者简介：
- 基金信息：
  
  the Fund for Creative Research Groups of National Natural Science Foundation of China(31921003)
- DOI：10.16016/j.1000-5404.202102092
  CLC： R741.04;R743.34;R749.13
- Received：20 February 2021，
  
  Revised：2021-06-04，
  
  Published：15 August 2021
- 稿件说明：
移动端阅览
Shiyi ZUO, Juan SUN, Zhenzhen CHEN, et al. Correlation analysis of basic vital signs and behavioral score of disorders of consciousness in patients with brainstem hemorrhage[J]. Journal of Third Military Medical University, 2021, 43(15): 1418-1423.
DOI：

Shiyi ZUO, Juan SUN, Zhenzhen CHEN, et al. Correlation analysis of basic vital signs and behavioral score of disorders of consciousness in patients with brainstem hemorrhage[J]. Journal of Third Military Medical University, 2021, 43(15): 1418-1423. DOI： 10.16016/j.1000-5404.202102092.

摘要

目的

研究脑干出血患者基本生命体征与意识障碍行为学评分的相关性。

方法

从陆军军医大学第二附属医院神经外科2015年1月至2020年11月收治的375例脑干出血患者中筛选出73例，依据入院后24 h内的格拉斯哥昏迷量表(Glasgow Coma Scale

GCS)评分将其分为无意识障碍组(

=38)和重度意识障碍组(

=35)，比较入院后24 h内、出院前24 h内两个时期的GCS评分及GCS中应答能力、行为认知能力、肢体对疼痛刺激反应、自行睁眼反应等行为学表现，以及腋测体温、脉搏频率和呼吸频率变化情况。根据是否有前述的行为学表现，又将重度意识障碍组患者分为有行为表现组(

=21)与无行为表现组(

=14)，比较二者的腋测体温、脉搏频率和呼吸频率变化。将无意识障碍组、重度意识障碍组入院后24 h内、出院前24 h内的GCS评分与同时期的腋测体温、脉搏频率和呼吸频率进行相关性和差异性分析。

结果

在入院后24 h内、出院前24 h内两个时期，与无意识障碍组相比，重度意识障碍组患者的GCS评分更低，腋测体温和脉搏频率频率均显著升高(

0.05)；但入院后24 h内的呼吸频率两组间差异无统计学意义，而出院前24 h内呼吸频率则在重度意识障碍组患者显著升高(

0.05)。另外，无意识障碍组、重度意识障碍组两个时期的GCS评分与同时期的腋测体温、脉搏频率和呼吸频率差异均无统计学意义。重度意识障碍患者有行为表现组与无行为表现组在两个时期的腋测体温、呼吸频率、入院后24 h内脉搏频率差异均无统计学意义，但无行为表现组出院前24 h内的脉搏频率较有行为表现组明显升高(

0.05)。

结论

脑干出血患者基本生命体征与意识障碍行为学评分紧密相关，其中入院后24 h内和出院前24 h内的腋测体温、脉搏频率的升高与意识障碍患者GCS评分降低呈显著正相关。

Abstract

Objective

To study the correlation of basic vital signs with behavioral score of disorders of consciousness (DOC) in patients with brainstem hemorrhage.

Methods

A total of 73 patients with brain stem hemorrhage were screened out from 375 patients admitted to the Department of Neurosurgery of the Second Affiliated Hospital of Army Medical University from January 2015 to November 2020. According

to the Glasgow Coma Scale (GCS) score within 24 h after admission

they were divided into normal consciousness group (

=38) and severe DOC group (

=35). Their GCS score

GCS response ability

behavioral cognitive ability

limb response to pain stimulation and eye-opening response

as well as axillary temperature

pulse rate and respiratory rate were compared between the 2 groups at the 2 time points

that is

24 h after admission and 24 h before discharge. According to the behavioral responses mentioned above

the patients out of severe DOC group were further assigned into the subgroup having behavioral responses (behavioral subgroup

=21) and the subgroup without (non-behavioral subgroup

=14)

and the changes of axillary temperature

pulse rate and respiratory rate were compared with between them. The correlations and differences among the GCS scores and axillary body temperature

pulse rate and respiratory rate were analyzed between the normal consciousness group and the severe DOC group during the 24 h after admission and 24 h before discharge.

Results

In 24 h after admission and 24 h before discharge

the patients in the severe DOC group had significantly lower GCS scores and higher mean temperature and pulse rate than the normal consciousness group (

0.05). However

there was no statistical difference in the mean respiratory rate within 24 h after admission between the 2 groups (

0.05)

and the rate within 24 h before discharge was obviously higher in the severe DOC group than another group (

0.05). In addition

no statistical correlations were observed among GCS scores and axillary temperature

pulse rate and respiratory rate in the 2 groups at the 2 time points (

0.05). There were no significant differences in the mean value of axillary temperature

pulse rate and respiratory rate within 24 h after admission between the

behavioral and non-behavioral subgroups (

0.05)

but the mean pulse rate within 24 h before discharge in the latter subgroup was significantly higher than that in the behavioral subgroups (

0.05).

Conclusion

The basic vital signs of patients with brainstem hemorrhage are closely correlated with the behavioral GCS scores of DOC

and among these signs

increased axillary temperature and pulse rate within 24 h after admission and 24 h before discharge are positively correlated with decreased GCS scores of patients with severe DOC.

关键词

Keywords

references

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