Hongbo CHEN, Junhui WU, Yiqun WU, et al. Epidemiology of major comorbidities in adult patients with osteoarthritis in Beijing from 2015 to 2017[J]. Journal of Third Military Medical University, 2021, 43(12): 1103-1108.
DOI:
Hongbo CHEN, Junhui WU, Yiqun WU, et al. Epidemiology of major comorbidities in adult patients with osteoarthritis in Beijing from 2015 to 2017[J]. Journal of Third Military Medical University, 2021, 43(12): 1103-1108. DOI: 10.16016/j.1000-5404.202101143.
Epidemiology of major comorbidities in adult patients with osteoarthritis in Beijing from 2015 to 2017
To explore the epidemiological status and related factors for comorbidities of osteoarthritis (OA) among adult residents in Beijing.
Methods
2
Based on the medical records of all designated medical institutes in Beijing from 2015 to 2017
relevant data of adult OA patients were collected
and the prevalence of major comorbidities such as type 2 diabetes
depression
hypertension and dyslipidemia in this population was statistically described and analyzed
and the differences among populations with different sociodemographic characteristics were compared.
Results
2
A total of 3 048 304 adult OA patients were included
with a mean age of 58.2±14.5 years
and females accounting for 62.2%. 79.8% of the subjects had at least 1 comorbidity
with the males (82.6%) having a higher prevalence than the females (78.1%). The prevalence of OA comorbidities was increased with age and statistically significant among different age groups (
P
<
0.05). The prevalence in the patients living in the rural areas (82.7%) was
higher than that in urban areas (78.8%). The top 4 most common comorbidities were hypertension (68.0%)
dyslipidemia (63.8%)
type 2 diabetes (36.3%)
and depression (8.2%). The males were more likely to suffer from hypertension
dyslipidemia and type 2 diabetes
while the females from depression. The proportion of OA patients with 1
2
3 or more kinds of comorbidities was 17.7%
30.7%
31.4% respectively. The risk factors for OA comorbidities included: male (
OR
=1.15
95%
CI
: 1.14~1.16)
≥55 years old (
OR
=1.07
95%
CI
: 1.07~1.07)
living in rural areas (
OR
=1.66
95%
CI
: 1.64~1.67)
and taking manual labor (
OR
=1.02
95%
CI
: 1.01~1.02).
Conclusion
2
The adult OA patients in Beijing have relatively high prevalences of comorbidities
including dyslipidemia
hypertension
type 2 diabetes and other diseases. More attention should be paid to the middle-aged and elderly patients and those in rural areas.
关键词
Keywords
references
HUNTER D J, BIERMA-ZEINSTRA S. Osteoarthritis[J]. Lancet, 2019, 393 (10182): 1745-1759.
HUNTER D J, SCHOFIELD D, CALLANDER E. The individual and socioeconomic impact of osteoarthritis[J]. Nat Rev Rheumatol, 2014, 10(7): 437-441. DOI: 10.1038/nrrheum.2014.44.
LONG X T. Timing and efficiency for selective joint replacement surgery for senile knee osteoarthritis[J]. J Third Mil Med Univ, 2012, 34(24): 2522-2525. DOI: 10.16016/j.1000-5404.2012.24.024.
CAUGHEY G E, VITRY A I, GILBERT A L, et al . Prevalence of comorbidity of chronic diseases in Australia[J ] . BMC Public Health, 2008, 8: 221. DOI: 10.1186/1471-2458-8-221.
STUBBS B, ALUKO Y, MYINT P K, et al . Prevalence of depress ive symptoms and anxiety in osteoarthritis: a systematic review and meta-analysis[J ] . Age Ageing, 2016, 45(2): 228-235. DOI: 10.1093/ageing/afw001.
LOUATI K, VIDAL C, BERENBAUM F, et al . Association between diabetes mellitus and osteoarthritis: systematic literature review and meta-analysis[J ] . RMD Open, 2015, 1(1): e000077. DOI: 10.1136/rmdopen-2015-000077.
CALDERS P, VAN GINCKEL A. Presence of comorbidities and prognosis of clinical symptoms in knee and/or hip osteoarthritis: a systematic review and meta-analysis[J]. Semin Arthritis Rheum, 2018, 47(6): 805-813. DOI: 10.1016/j.semarthrit.2017.10.016.
NEOGI T. The epidemiology and impact of pain in osteoarthritis[J]. Osteoarthr Cartilage, 2013, 21(9): 1145-1153. DOI: 10.1016/j.joca.2013.03.018.
TANG X, WANG S, ZHAN S, et al . The prevalence of symptomatic knee osteoarthritis in China: results from the China health and retirement longitudinal study[J ] . Arthr Rheumatol, 2016, 68(3): 648-653. DOI: 10.1002/art.39465.
ZULLIG L L, BOSWORTH H B, JEFFREYS A S, et al . The association of comorbid conditions with patient-reported out comes in Veterans with hip and knee osteoarthritis[J ] . Clin Rheumatol, 2015, 34(8): 1435-1441.
HAWKER G A, CROXFORD R, BIERMAN A S, et al . Osteoarthritis-related difficulty walking and risk for diabetes complications[J ] . Osteoarthr Cartilage, 2017, 25(1): 67-75. DOI: 10.1016/j.joca.2016.08.003.
VERONESE N, COOPER C, REGINSTER J Y, et al . Type 2 diabetes mellitus and osteoarthritis[J ] . Semin Arthritis Rheum, 2019, 49(1): 9-19. DOI: 10.1016/j.semarthrit.2019.01.005.
Australian Bureau of Statistics. National health survey: Summary of results 2004-2005[EB/OL]. [2006-02-27]. https://www.abs.gov.au/AUSSTATS/abs@.nsf/DetailsPage/4364.02004-05?OpenDocument.
KENDZERSKA T, KING L K, LIPSCOMBE L, et al . The impact of hip and knee osteoarthritis on the subsequent risk of incident diabetes: a population-based cohort study[J ] . Diabetologia, 2018, 61(11): 2290-2299. DOI: 10.1007/s00125-018-4703-2.
WANG L M, GAO P, ZHANG M, et al . Prevalence and ethnic pattern of diabetes and prediabetes in China in 2013[J ] . JAMA, 2017, 317(24): 2515-2523. DOI: 10.1001/jama.2017.7 596.
BAUDART P, LOUATI K, MARCELLI C, et al . Association between osteoarthritis and dyslipidaemia: a systematic literature review and meta-analysis[J ] . RMD Open, 2017, 3(2): e000442. DOI: 10.1136/rmdopen-2017-000442.
ZENG Y B, YUAN Z P, FANG Y. Healthcare seeking behavior among Chinese older adults: patterns and predi cting factors[J]. Chin J Heal Stat, 2020, 37(2): 199-205.
XIONG W, GAO P. Aging society: pay attention to critical illness in the elderly[J]. J Third Mil Med Univ, 2019, 41(19): 1881-1884. DOI: 10.16016/j.1000-5404.201908223.
YANG Q P, FAN N, HE R J. Gender differences and related factors of knee osteoarthritis[J]. Chin J Gerontol, 2016, 36(1): 144-146. DOI: 10.3969/j.issn.1005-9202.2016.01.068.
Epidemiological status and characteristics of common comorbidities of type 2 diabetes mellitus among 1.15 million patients in Beijing area
Cold exposure exacerbates osteoarthritis via synergistic muscle atrophy and fibrosis
Intelligent cloud platform follow-up model improves joint range of motion and reduces follow-up costs after total knee arthroplasty: A retrospective cohort study
Predictive value of TyG-BMI, AIP, and postprandial glucose excursion for sarcopenia in patients with type 2 diabetes mellitus
Renal protective effect of equol on type 2 diabetic rats
Related Author
Jiating WANG
Zijing WANG
Yiqun WU
Junhui WU
Yao WU
Xiaowen WANG
Siyue WANG
Mengying WANG
Related Institution
Department of Epidemiology and Biostatistics, School of Public Health, Peking University
Department of War Wound Tissue Repair and Rehabilitation Medicine,Daping Hospital,Army Medical University
Hospital of PLA Army
Center of Sports Medicine
Center of Joint Surgery, First Affiliated Hospital, Army Medical University (Third Military Medical University), Chongqing