Sterilization effectiveness of hydrogen peroxide low temperature plasma on rigid gas permeable contact trial lens

Li CHEN; Bo LIU; Wei YANG; Libing SONG; Min HE; Shujia HUO

doi:10.16016/j.1000-5404.202101067

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Sterilization effectiveness of hydrogen peroxide low temperature plasma on rigid gas permeable contact trial lens

Clinical Medicine | 更新时间：2026-01-09

- Sterilization effectiveness of hydrogen peroxide low temperature plasma on rigid gas permeable contact trial lens
- Journal of Third Military Medical University Vol. 43, Issue 13, Pages: 1275-1279(2021)
- 作者机构：
  
  400038 重庆，陆军军医大学(第三军医大学)第一附属医院眼科
- 作者简介：
- 基金信息：
  
  the Joint Project of Medical Science Research of Chongqing Science and Technology Commission and Chongqing Health Commission(2021MSXM068)
- DOI：10.16016/j.1000-5404.202101067
  CLC： R187.2;R778.3
- Received：07 January 2021，
  
  Revised：2021-03-26，
  
  Published：15 July 2021
- 稿件说明：
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Li CHEN, Bo LIU, Wei YANG, et al. Sterilization effectiveness of hydrogen peroxide low temperature plasma on rigid gas permeable contact trial lens[J]. Journal of Third Military Medical University, 2021, 43(13): 1275-1279.
DOI：

Li CHEN, Bo LIU, Wei YANG, et al. Sterilization effectiveness of hydrogen peroxide low temperature plasma on rigid gas permeable contact trial lens[J]. Journal of Third Military Medical University, 2021, 43(13): 1275-1279. DOI： 10.16016/j.1000-5404.202101067.

摘要

目的

对比过氧化氢低温等离子灭菌法与传统镜片消毒方法对硬性角膜接触镜试戴片的消毒效果。

方法

选择2020年4-8月来我院验配硬性角膜接触镜患者使用后的试戴片90片。根据镜片消毒方式分为3组，A组采用改良后的过氧化氢低温等离子灭菌法(30片)，B组采用传统护理液消毒(30片)，C组采用高分子材料注塑制成的抗菌镜盒消毒(30片)。采用美国赛默飞Versa TREK 528全自动微生物培养系统检测试戴片保存液，共培养5 d，评估镜片消毒效果，每月检测1次，连续检测3个月。裂隙灯检查眼表情况，问卷调查评估试戴后舒适度。

结果

A组细菌培养均为阴性，灭菌效果100.0%；B组2次培养出现异常菌群，灭菌效果97.7%；C组1次培养出现异常菌群，灭菌效果98.9%。3种消毒方法差异无统计学意义。角膜健康检查与舒适度问卷调查显示3组消毒方法差异均无统计学意义。

结论

过氧化氢低温等离子灭菌法对硬性角膜接触镜试戴片消毒彻底，不仅可保障患者的安全，而且流程简洁，值得推广。

Abstract

Objective

To compare the disinfection effect of hydrogen peroxide low temperature plasma sterilization and traditional lens disinfection on rigid gas permeable contact lens (RGP)

so as to improve the clinical management procedure of RGP trial lens.

Methods

A total of 90 RGP trial lenses used by patients in our hospital from April to August 2020 were collected and randomly divided into 3 groups. Group A was treated with modified hydrogen peroxide low temperature plasma sterilizing method (

=30); group B was disinfected with conventional conditioning solution (

=30); and group C was sterilized with anti-bacterial case made of polymer injection material (

=30). The preserving solution of the 3 groups was respectively cultured for 5 d and then tested with the automatic microbial culture system of American Simmer TREK 528

and a comparison of the sterilization effect was made among the groups. The test was performed once a month for 3 months. Moreover

patients' ocular surface condition was examined with a slit lamp

and the comfort level after wearing was evaluated through questionnaire survey.

Results

The bacteria culture of group A was negative with the sterilization effect of 100.0%

while abnormal bacteria were detected 2 cases in group B and 1 case in group C

with the disinfection rates of 97.7% and 98.9%

respectively

though there was no statistical difference among the 3 disinfection methods. In addition

the results of corneal examination and comfort questionnaire survey showed no statistical difference among the groups as well.

Conclusion

Hydrogen peroxide low-temperature plasma sterilization has a thorough disinfection effect with a safe and simple procedure

and is worth popularizing.

关键词

Keywords

references

FAN D S,LAM D S, LAM R F, et al . Prevalence, incidence, and progression of myopia of school children in Hong Kong[J ] . Invest Ophthalmol Vis Sci, 2004, 45(4): 1071-1075. DOI:10.1167/iovs.03-1151.

姜珺. 近视管理白皮书(2019)[J]. 中华眼视光学与视觉科学杂志, 2019, 21(3): 161-165. DOI:10.3760/cma.j.issn.1674-845X.2019.03.001.

JIANG J. Expert consensus on myopia management white paper (2019)[J]. Chin J Optom Ophthalmol Vis Sci, 2019, 21(3): 161-165. DOI:10.3760/cma.j.issn.1674-845X.2019.03.001.

中华医学会眼科学分会眼视光学组. 角膜塑形术的临床风险防控指南(2017)[J]. 中华眼视光学与视觉科学杂志, 2017, 19(8): 449-453. DOI:10.3760/cma.j.issn.1674-845X.2017.08.001.

Chinese Optometric of Chinese Ophthalmological Society of CMA. Guideline for prevention and control of clinical risk in orthokeratology (2017)[J]. Chin J Optom Ophthalmol Vis Sci, 2017, 19(8): 449-453. DOI:10.3760/cma.j.issn.1674-845X.2017.08.001.

国际角膜塑形学会亚洲分会. 中国角膜塑形用硬性透气接触镜验配管理专家共识(2016年)[J]. 中华眼科杂志, 2016, 52(5): 325-327. DOI:10.3760/cma.j.issn.0412-4081.2016.05.002.

International Academy of Orthokeratology-Asia. Chinese expert consensus on the management of rigid gas permeable contact lenses for orthokeratology (2016)[J]. Chin J Ophthalmol, 2016, 52(5): 325-327. DOI:10.3760/cma.j.issn.0412-4081.2016.05.002.

刘素珍, 罗绍芳, 侯军文, 等. 低温等离子灭菌器在角膜塑形镜灭菌中的应用效果[J]. 中国当代医药, 2019, 26(24): 150-153. DOI:10.3969/j.issn.1674-4721.2019.24.045.

LIU S Z, LUO S F, HOU J W, et al . Application effect of low temperature plasma sterilizer in orthokeratology sterilization[J ] . China Mod Med, 2019, 26(24): 150-153. DOI:10.3969/j.issn.1674-4721.2019.24.045.

励秀武. 过氧化氢等离子体低温灭菌器规范应用研究进展[J]. 中国消毒学杂志, 2018, 35(8): 611-614. DOI:10.11726/j.issn.1001-7658.2018.08.018.

LI X W. Research progress on application of hydrogen peroxide plasma low temperature sterilizer[J]. Chin J Disinfect, 2018, 35(8): 611-614. DOI:10.11726/j.issn.1001-7658.2018.08.018.

王星宇, 刘陇黔. 角膜塑形镜使用中镜盒微生物污染的危险因素[J]. 眼科学报, 2020, 35(1): 22-27. DOI:10.3978/j.issn.1000-4432.2020.03.01.

WANG X Y, LIU L Q. Risk factors of micro-organisms contamination of lens cases in Ortho-K wearing[J]. Eye Sci, 2020, 35(1): 22-27. DOI:10.3978/j.issn.1000-4432.2020.03.01.

王庆玲, 梁冰. Versa TREK血培养系统的临床应用及评价[J]. 实用医药杂志, 2017, 34(2): 116-118, 121. DOI:10.14172/j.issn1671-4008.2017.02.007.

WANG Q L, LIANG B. Clinical application and evaluation of Versa TREK blood culture system[J]. Pract J Med Pharm, 2017, 34(2): 116-118, 121. DOI:10.14172/j.issn1671-4008.2017.02.007.

陈洁, 吕帆. 硬性透气性角膜接触镜对儿童近视进展的延缓作用[J]. 眼视光学杂志, 2006, 8(1): 66-68. DOI:10.3760/cma.j.issn.1674-845X.2006.01.022.

CHEN J, LYU F. Review: RGP correction and its effect on slow down of childhood's myopia progression[J]. Chin J Optom Ophthalmol, 2006, 8(1): 66-68. DOI:10.3760/cma.j.issn.1674-845X.2006.01.022.

HU X J, SHI G S, LIU H, et al . Microbial contamination of rigid gas permeable (RGP) trial lenses and lens cases in China[J ] . Curr Eye Res, 2020, 45(5): 550-555. DOI:10.1080/02713683.2019.1687726.

CARNT N, SAMARAWICKRAMA C, WHITE A, et al . The diagnosis and management of contact lens-related microbial keratitis[J ] . Clin Exp Optom, 2017, 100(5): 482-493. DOI:10.1111/cxo.12581.

SAUER A, MEYER N, BOURCIER T, et al . Risk factors for contact lens-related microbial keratitis: a case-control multicenter study[J ] . Eye Contact Lens, 2016, 42(3): 158-162. DOI:10.1097/icl.0000000000000180.

王帅, 王嫱怡, 李玉瑭, 等. 接触镜储存盒不同处理方式对常见接触镜相关角膜炎病原菌生物被膜的清除作用[J]. 中华实验眼科杂志, 2020, 38(3): 175-180.

WANG S, WANG Q Y, LI Y T, et al . Different contact lens case treatment methods for the elimination of pathogen biofilms associated wit h contact lens related microbial keratitis[J ] . Chin J Exp Ophthalmol, 2020, 38(3): 175-180.

何惠燕, 黄凤玉, 吴雪花, 等. 三种生物指示物监测过氧化氢低温等离子灭菌的效果比较[J]. 中华医院感染学杂志, 2020, 30(14): 2236-2240.

HE H Y, HUANG F Y, WU X H, et al . Surveillance of effects of hydrogen peroxide low-temperature plasma sterilization with three kinds of biological indicators: a comparative study[J ] . Chin J Nosocomiology, 2020, 30(14): 2236-2240.

吕帆, 谢培英. 角膜接触镜学[M]. 北京: 人民卫生出版社, 2004: 63-64.

LYU F, XIE P Y. Contact Lens[M]. Beijing: People's Medical Publishing House, 2004: 63-64.

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