Correlation of metabolic syndrome and its components with arterial stiffness among rural residents in Beijing

Zijing WANG; Yiqun WU; Yao WU; Mengying WANG; Xiaowen WANG; Junhui WU; Siyue WANG; Jiating WANG; Dafang CHEN; Tao WU; Yonghua HU

doi:10.16016/j.1000-5404.202101015

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Correlation of metabolic syndrome and its components with arterial stiffness among rural residents in Beijing

Monographic Reports: | 更新时间：2026-01-09

- Correlation of metabolic syndrome and its components with arterial stiffness among rural residents in Beijing
- Journal of Third Military Medical University Vol. 43, Issue 12, Pages: 1109-1116(2021)
- 作者机构：
  
  100191 北京，北京大学公共卫生学院流行病与卫生统计学系
- 作者简介：
- 基金信息：
  
  the National Natural Science Foundation of China(81872695);the National Natural Science Foundation of China(81703291)
- DOI：10.16016/j.1000-5404.202101015
  CLC： R181.3;R543.5;R589.9
- Received：04 January 2021，
  
  Revised：2021-02-17，
  
  Published：30 June 2021
- 稿件说明：
移动端阅览
Zijing WANG, Yiqun WU, Yao WU, et al. Correlation of metabolic syndrome and its components with arterial stiffness among rural residents in Beijing[J]. Journal of Third Military Medical University, 2021, 43(12): 1109-1116.
DOI：

Zijing WANG, Yiqun WU, Yao WU, et al. Correlation of metabolic syndrome and its components with arterial stiffness among rural residents in Beijing[J]. Journal of Third Military Medical University, 2021, 43(12): 1109-1116. DOI： 10.16016/j.1000-5404.202101015.

摘要

目的

探讨代谢综合征(metabolism syndrome

MS)及其组分与动脉硬化的关系，并分析其性别差异。

方法

对6 737名北京市农村居民进行问卷调查、体格检查和血生化检测。MS定义采用中华医学会糖尿病学分会2017年修订版标准。动脉硬化定义为肱踝脉搏波传导速度≥1 700 cm/s。采用多因素Logistic回归分析MS及其组分与动脉硬化的相关性。

结果

研究对象中动脉硬化、MS患者占比分别为41.7%和64.4%。MS患者动脉硬化风险是非患者的2.36倍(95%

: 2.06~2.71)；除高密度脂蛋白胆固醇降低外，其余MS组分均与动脉硬化显著相关，相关性由大到小依次为高血压、高血糖、甘油三酯升高和中心性肥胖。MS与动脉硬化的相关性在女性中强于男性，差异有统计学意义(

=0.023)。

结论

MS与动脉硬化风险增加有关，高血压是影响最大的组分；MS对动脉硬化的影响在女性中更强。

Abstract

Objective

To investigate the correlation of metabolic syndrome (MS) and its components with arterial stiffness

and to analyze the gender difference.

Methods

Questionnaires

physical examinations and blood biochemical tests were conducted among 6 737 rural residents in Beijing. The diagnosis of MS is identified based on the 2017 modified standard of Diabetes Society of Chinese Medical Association

and arterial stiffness is defined as brachia-ankle pulse wave velocity (BAPWV) ≥1 700 cm/s. Multivariate Logistic regression analysis was used to analyze the correlation of MS and its components with arterial stiffness.

Results

In the subjects

arterial stiffness and MS patients accounted for 41.7% and 64.4%

respectively. The MS patients was at a risk of arterial stiffness by 2.36-fold (95%

: 2.06~2.71) higher than that in the non-MS subjects. Except for the reduced high density lipoprotein-cholesterol (HDL-C)

the other MS components were all significantly correlated with arterial stiffness

including elevated blood pressure

blood glucose and triglyceride

and central obesity. The correlation between MS and arterial stiffness was stronger in the women than the men.

Conclusion

MS is correlated with an increased risk of arterial stiffness

with elevated blood pressure being the most significant component. The effect of MS and its components on arterial stiffness is stronger in female population.

关键词

Keywords

references

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