Diagnostic efficacy of modified DIXON magnetic resonance angiography in axillary lymph node resectability for breast cancer patients

Yuchuan TAN; Fajin LYU; Yineng ZHENG; Lu YANG; Hanli DAN; Wei LI

doi:10.16016/j.1000-5404.202010061

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Diagnostic efficacy of modified DIXON magnetic resonance angiography in axillary lymph node resectability for breast cancer patients

更新时间：2026-01-09

- Diagnostic efficacy of modified DIXON magnetic resonance angiography in axillary lymph node resectability for breast cancer patients
- Journal of Third Military Medical University Vol. 43, Issue 6, Pages: 541-546(2021)
- 作者机构：
- 作者简介：
- 基金信息：
- DOI：10.16016/j.1000-5404.202010061
  CLC：
- Received：14 October 2020，
  
  Published：30 March 2021
- 稿件说明：
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Yuchuan TAN, Fajin LYU, Yineng ZHENG, et al. Diagnostic efficacy of modified DIXON magnetic resonance angiography in axillary lymph node resectability for breast cancer patients[J]. Journal of Third Military Medical University, 2021, 43(6): 541-546.
DOI：

Yuchuan TAN, Fajin LYU, Yineng ZHENG, et al. Diagnostic efficacy of modified DIXON magnetic resonance angiography in axillary lymph node resectability for breast cancer patients[J]. Journal of Third Military Medical University, 2021, 43(6): 541-546. DOI： 10.16016/j.1000-5404.202010061.

摘要

Abstract

Objective

To evaluate the diagnostic efficacy of modified DIXON magnetic resonance angiography (mDIXON-MRA) in the possibility of axillary lymph node dissection for patients with breast cancer.

Methods

A retrospective case-control trial was conducted on 77 patients with breast cancer who underwent MRI examination in the Affiliated Tumor Hospital of Chongqing University from December 2018 to January 2020. All the patients preoperatively received mDIXON-MRA

T1 weighted imaging (T1WI)

T2 weighted imaging (T2WI)

fat-suppressed T2-weighted imaging (T2WI-FS)

and contrast-enhanced T1 weighted imaging (T1WI-CE) on the axillary region. After image post-processing and reconstruction

the obtained images were analyzed and scored by 2 radiologists respectively according to the film reviewing criteria. The resectability of lymph nodes was evaluated by judging the relationship between lymph nodes and peripheral blood vessels

and the difference of scoring the images from different sequences was compared and analyzed. Receiver operating characteristic (ROC) curve was plotted based on the intraoperative judgment of the surgeon

and then the effectiveness of different sequences was analyzed in diagnosis of the resectability of enlarged lymph nodes in breast cancer patients.

Results

Mean score of the images from mDIXON-MRA

T1WI

T2WI

T2WI-FS and T1WI-CE were 2.01±0.97

2.22±1.05

2.22±1.07

2.42±1.06

and 2.53±1.02

respectively. And significant differences were observed in the diagnostic effectiveness of axillary lymph nodes resectability based on the 5 sequences (

0.05). The area under the curve (AUC) of mDIXON-MRA sequence took the highest (0.854) among the 5 sequences

which was equivalent to the area after the combination of multiple sequences

showing the best evaluation efficiency.

Conclusion

mDIXON-MRA presents the highest clinical diagnostic value among various MRI sequences in the evaluation of the resectability of axillary lymph nodes in breast cancer patients

with its diagnostic efficiency similar to that of combined application of multiple sequences.

关键词

Keywords

references

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