Association of exposure to environmental gaseous pollutants in Chongqing with semen quality and sex hormone levels in Chongqing young men

Ying XIONG; Furong WANG; Qing CHEN; Huan YANG; Wenzheng ZHOU; Dan ZHANG; Jia CAO; Niya ZHOU

doi:10.16016/j.1000-5404.202010001

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Association of exposure to environmental gaseous pollutants in Chongqing with semen quality and sex hormone levels in Chongqing young men

更新时间：2026-01-09

- Association of exposure to environmental gaseous pollutants in Chongqing with semen quality and sex hormone levels in Chongqing young men
- Journal of Third Military Medical University Vol. 43, Issue 1, Pages: 10-16(2021)
- 作者机构：
- 作者简介：
- 基金信息：
  
  the Key Program of National Natural Science Foundation of China(81630087);the National Key Research and Development Program of China(2017YFC1002001)
- DOI：10.16016/j.1000-5404.202010001
  CLC：
- Received：01 October 2020，
  
  Published：15 January 2021
- 稿件说明：
移动端阅览
Ying XIONG, Furong WANG, Qing CHEN, et al. Association of exposure to environmental gaseous pollutants in Chongqing with semen quality and sex hormone levels in Chongqing young men[J]. Journal of Third Military Medical University, 2021, 43(1): 10-16.
DOI：

Ying XIONG, Furong WANG, Qing CHEN, et al. Association of exposure to environmental gaseous pollutants in Chongqing with semen quality and sex hormone levels in Chongqing young men[J]. Journal of Third Military Medical University, 2021, 43(1): 10-16. DOI： 10.16016/j.1000-5404.202010001.

摘要

Abstract

Objective

To investigate the effects of atmospheric gaseous pollutants SO

CO and O

on the reproductive endocrine system of male college students.

Methods

Established cohort of the male reproductive health in Chongqing college students (MARHCS) study. A total of 796 subjects were recruited to complete the baseline survey in 2013

and then followed up in 2014 and 2015. Their semen parameters

sperm DNA damage

and serum sex hormone levels were detected. Air pollution data and meteorological data were also collected during the study period. The mixed effect model was used to analyze the associations of exposure to SO

and CO with semen routine parameters

sperm DNA damage indexes and sex hormone levels.

Results

There were no significant differences in sperm motility and serum progesterone level between the 3 investigations. But statistical differences were observed in semen volume

sperm density

total sperm count

sperm motility and normal sperm morphology

and high DNA stainability (HDS) between the 3 investigations (

0.05). So were in the serum levels of estradiol

luteinizing hormone (LH)

prolactin and testosterone. The results of the mixed effect model showed that significant negative correlations were seen in SO

concentration with serum prolactin and progesterone levels

in O

concentration with follicle stimulating hormone (FSH) and testosterone to estradiol ratio (T/E

)

in NO

with sperm normal morphology rate

and in CO with FSH level. After Bonferroni multiple correction

the differences were still statistically significant (corrected

0.05). In addition

concentration was positively correlated with sperm motility (

=4.88; 95%

: 2.60~7.22; corrected

0.05) and normal sperm morphology rate (

=7.28; 95%

: 3.44~11.27; corrected

0.05). So were the concentration of NO

with serum FSH

LH and testosterone levels (corrected

0.05).

Conclusion

Exposure to gaseous pollutants SO

and CO might affect the semen quality and reproductive hormone levels in young men.

关键词

Keywords

references

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