Safety assessment of preoperative autologous blood donation in Rh(D)-negative pregnant women

Xiaoli YAN; Hongyu LI; Heying LIU; Yahan FAN; Wenxi ZHANG; Dan WANG; Qing CHANG

doi:10.16016/j.1000-5404.202004266

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Safety assessment of preoperative autologous blood donation in Rh(D)-negative pregnant women

Clinical Medicine | 更新时间：2026-01-09

- Safety assessment of preoperative autologous blood donation in Rh(D)-negative pregnant women
- Journal of Third Military Medical University Vol. 42, Issue 18, Pages: 1848-1852(2020)
- 作者机构：
  
  1.400038 重庆，陆军军医大学(第三军医大学)第一附属医院:妇产科
  2.400038 重庆，陆军军医大学(第三军医大学)第一附属医院:输血科
- 作者简介：
- 基金信息：
- DOI：10.16016/j.1000-5404.202004266
  CLC： R457.11;R714.3;R715.7
- Received：24 April 2020，
  
  Revised：2020-06-05，
  
  Published：30 September 2020
- 稿件说明：
移动端阅览
Xiaoli YAN, Hongyu LI, Heying LIU, et al. Safety assessment of preoperative autologous blood donation in Rh(D)-negative pregnant women[J]. Journal of Third Military Medical University, 2020, 42(18): 1848-1852.
DOI：

Xiaoli YAN, Hongyu LI, Heying LIU, et al. Safety assessment of preoperative autologous blood donation in Rh(D)-negative pregnant women[J]. Journal of Third Military Medical University, 2020, 42(18): 1848-1852. DOI： 10.16016/j.1000-5404.202004266.

摘要

目的

分析Rh(D)阴性孕妇预存式自体输血(preoperativeautologous blood donation，PABD)妊娠结局及新生儿情况。

方法

收集2015年-2019年在我院分娩的349例Rh(D)阴性孕妇的临床资料，对PABD组和无PABD组的母儿结局进行对比分析。

结果

349例Rh(D)阴性孕妇中204例(58.5%)行PABD，采血时间距分娩时间3~34(14.0±0.5)d。自体血回输35例，回输比例17.2%；PABD组与无PABD组之间分娩孕周、分娩方式、产后出血量、新生儿脐动脉血气指标相比差异无统计学意义(

0.05)；孕妇采血过程中母儿无不良反应；PABD组采血前后血细胞相关指标比较差异无统计学意义(

0.05)。

结论

对Rh(D)阴性等稀有血型孕妇预存式自体输血方案安全可行，且经济成本低，应加强妊娠期系统管理、严格掌握适应证。

Abstract

Objective

To analyze the pregnancy and neonatal outcomes of Rh(D)-negative pregnant women who received preoperative autologous blood donation (PABD).

Methods

We retrospectively collected the clinical data of 349 Rh(D)-negative pregnant women delivered in our hospital between January

2015 and December

2019

and compared the maternal and neonatal outcomes between the women receiving PABD and those without PABD.

Results

Among the 349 Rh(D)-negative pregnant women

204 (58.5%) received PABD

and the interval between blood collection and delivery averaged 14.0±0.5 d (range 3~34 days); 35 (17.2%) of the women with PABD had autologous blood transfusion. The gestational weeks

delivery mode

postpartum blood loss

or neonatal umbilical artery blood gas index did not differ significantly between the women with and without PABD (

0.05). In the women with PABD

no adverse reactions occurred during blood collection

and no significant changes were found in blood cell indexes after blood collection (

0.05).

Conclusion

PABD is safe and cost-effective in pregnant women with rare blood types such as Rh(D) negative women.

关键词

Keywords

references

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