Analysis of risk factors of enterostomy in infants with Hirschsprung's disease

Qiuping LEI; Jian CAO; Xiaoqing LI; Dekai ZHOU; Yi WANG; Yun HE

doi:10.16016/j.1000-5404.202001043

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Analysis of risk factors of enterostomy in infants with Hirschsprung's disease

Clinical Medicine | 更新时间：2026-01-09

- Analysis of risk factors of enterostomy in infants with Hirschsprung's disease
- Journal of Third Military Medical University Vol. 42, Issue 12, Pages: 1215-1219(2020)
- 作者机构：
  
  400014 重庆, 重庆医科大学附属儿童医院胃肠新生儿外科; 儿童发育疾病研究教育部重点实验室; 国家儿童健康与疾病临床医学研究中心; 儿童发育重大疾病国家国际科技合作基地; 儿科学重庆市重点实验室
- 作者简介：
- 基金信息：
  
  the Joint Project for Medical Scientific Research of Chongqing (Science and Technology Commission and Chongqing Health Commission(2019ZDXM021);the Natural Science Foundation of Chongqing(CSTC2018jcyjA0340)
- DOI：10.16016/j.1000-5404.202001043
  CLC： R181.32;R725.746.2;R726.569
- Received：06 January 2020，
  
  Revised：2020-02-04，
  
  Published：30 June 2020
- 稿件说明：
移动端阅览
Qiuping LEI, Jian CAO, Xiaoqing LI, et al. Analysis of risk factors of enterostomy in infants with Hirschsprung's disease[J]. Journal of Third Military Medical University, 2020, 42(12): 1215-1219.
DOI：

Qiuping LEI, Jian CAO, Xiaoqing LI, et al. Analysis of risk factors of enterostomy in infants with Hirschsprung's disease[J]. Journal of Third Military Medical University, 2020, 42(12): 1215-1219. DOI： 10.16016/j.1000-5404.202001043.

摘要

目的

探讨小婴儿先天性巨结肠肠造瘘的危险因素

为临床工作者做出适时判断提供参考

并提高对治疗时机的把握。

方法

回顾性分析2013年1月至2019年1月重庆医科大学附属儿童医院收治的201例小婴儿先天性巨结肠临床资料

通过单因素和多因素Logistic回归分析患儿一般资料、临床表现及实验室检验结果

总结分析肠造瘘的危险因素。

结果

本组肠造瘘发生率22.4%

经多因素Logistic回归分析发现血清白蛋白降低(

值=0.737

95%

=0.633~0.857

=0.000)

大便常规异常(

值=10.634

95%

=3.016~37.502

=0.000)

PCT

2 ng/mL(

值=9.954

95%

=2.517~39.368

=0.001)

右侧型先天性巨结肠(

值=4.307

95%

=1.417~13.092

=0.010)为本组患儿肠造瘘的危险因素。

结论

血清白蛋白降低、大便常规异常、PCT>2 ng/mL以及右侧型先天性巨结肠为小婴儿先天性巨结肠肠造瘘的危险因素。

Abstract

Objective

To explore the risk factors of enterostomy in infants with Hirschsprung' s disease (HSCR) to facilitate timely evaluation of the condition and the clinical decision-making on the timing of intervention.

Methods

We retrospectively analyzed the data of 201 infants diagnosed with HSCR in our hospital between January

2013 and January

2019. Univariate analysis and multivariate logistic regression were used to analyze the clinical data and laboratory test results of the patients to identify the risk factors of enterostomy.

Results

The incidence of enterostomy was 22.4% in these infants. Multivariate logistic regression analysis showed that lowered serum albumin level (

= 0. 737

95%

: 0. 633 - 0. 857

= 0. 000)

abnormal stool routine (

= 10. 634

95%

: 3. 016-37. 502

= 0. 000)

procalcitonin (PCT) level

2 ng /mL (

= 9. 954

95%

: 2. 517-39. 368

= 0. 001)

and right-sided HSCR (

= 4. 307

95%

: 1. 417-13. 092

= 0. 010) were risk factors for enterostomy in infants.

Conclusion

A lowed serum albumin level

abnormal stool routine

a PCT level > 2 ng /mL and right-sided HSCR are risk factors for enterostomy in infants with HSCR.

关键词

Keywords

references

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