Resting brain functional imaging of breast cancer survivors with fear of cancer recurrence based on ReHo method

Li PENG; Song XU; Xiaofei HU; Yuan XUE; Min LI

doi:10.16016/j.1000-5404.201912294

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Resting brain functional imaging of breast cancer survivors with fear of cancer recurrence based on ReHo method

更新时间：2026-01-09

- Resting brain functional imaging of breast cancer survivors with fear of cancer recurrence based on ReHo method
- Journal of Third Military Medical University Vol. 42, Issue 11, Pages: 1150-1154(2020)
- 作者机构：
- 作者简介：
- 基金信息：
- DOI：10.16016/j.1000-5404.201912294
  CLC：
- Received：31 December 2019，
  
  Published：15 June 2020
- 稿件说明：
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Li PENG, Song XU, Xiaofei HU, et al. Resting brain functional imaging of breast cancer survivors with fear of cancer recurrence based on ReHo method[J]. Journal of Third Military Medical University, 2020, 42(11): 1150-1154.
DOI：

Li PENG, Song XU, Xiaofei HU, et al. Resting brain functional imaging of breast cancer survivors with fear of cancer recurrence based on ReHo method[J]. Journal of Third Military Medical University, 2020, 42(11): 1150-1154. DOI： 10.16016/j.1000-5404.201912294.

摘要

Abstract

Objective

To investigate the characteristics of resting brain function in breast cancer survivors with fear of cancer recurrence.

Methods

A total of 59 breast cancer survivors were recruited by voluntary enrollment from Department of Breast and Thyroid Surgery

First Affiliated Hospital

Army Medical University during May and July 2017

and were divided into the low fear of cancer recurrence group (

=28) and high fear group (

=31) according to the results of Fear of Cancer Recurrence Inventory (FCRI). Their resting brain functional images were collected

and the differences of mean brain regional homogeneity (ReHo) map were compared between the 2 groups so as to i

nvestigate the consistency of spontaneous neuron activities in the brain.

Results

Compared to the low fear group

the ReHo value was increased in the left caudate nucleus and was decreased in the right anterior cuneiform lobe in the high fear group (

0.01). The value in the left caudate nucleus was negatively correlated with the total score of FCR (

=-0.501

0.05)

and that in the right anterior cuneiform lobe was positively with the total score (

=0.505

0.05).

Conclusion

Fear of cancer recurrence has significant effects on the consistency of spontaneous neuron activity in the left caudate nucleus and the right anterior cuneiform lobe in resting state

which may be related to the change of emotion and cognitive function of breast cancer survivors.

关键词

Keywords

references

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