Received:02 December 2019,
Published:30 April 2020
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Hao ZUO, Yuanjie JIANG, Jian SU, et al. Real-time three-dimensional transoesophageal echocardiography for diagnosis of pannus of prosthetic aortic valve[J]. Journal of Third Military Medical University, 2020, 42(8): 830-834.
Hao ZUO, Yuanjie JIANG, Jian SU, et al. Real-time three-dimensional transoesophageal echocardiography for diagnosis of pannus of prosthetic aortic valve[J]. Journal of Third Military Medical University, 2020, 42(8): 830-834. DOI: 10.16016/j.1000-5404.201912015.
Objective
2
To assess the value of real-time three-dimensional transoesophageal echocardiography (RT-3DTEE) in the diagnosis of pannus of prosthetic aortic valve.
Methods
2
A total of 89 patients with valve obstruction after receiving aortic valve replacement in our hospital were recruited between September
2017 and September
2019. All the patients underwent a second valve replacement
and the data of transthoracic echocardiography (TTE)
transesophageal echocardiography (TEE) and RT-3DTEE of these patients were analyzed.
Results
2
Of the 89 patients with valve obstruction
51 were diagnosed to have pannus with a mean thickness of 6.5±1.1 mm in the prosthetic aortic valve as confirmed by pathological examination of the surgical specimen. The thickness of the pannus measured by RT-3DTEE
TTE and TEE were 6.2±1.2 mm
5.1±1.2 mm
and 5.5±1.3 mm
respectively. The measurement by RT-3DTEE was well correlated with that on the surgical specimens (
P
<
0.01)
and the correlation was significantly better that of TTE and TEE (
P
<
0.05). The thickness of the pannus measured by RT-3
DTEE also differed significantly from that by TTE and TEE (
P
<
0.05). For the diagnosis of pannus
the sensitivity
specificity
positive predictive value and negative predictive value of RT-3DTEE were 84.3% 92.1%
93.5% and 81.4%
respectively
significantly higher than those of TTE (41.1%
89.5%
84.0% and 53.1%
respectively) and TEE (64.1%
89.5%
89.2% and 64.4%
respectively;
P
<
0.05). The pannus detected by RT-3DTEE occurred most commonly in the right anterior quadrant
with a circumference of 18.4±5.2 mm
an area of 0.79±0.28 cm
2
and a mean transaortic pressure gradient of 38±12 mmHg. The pannus area measured by RT-3DTEE was well correlated with the mean transaortic pressure gradient of the prosthetic valve; the degree of valve occlusion could be assessed based on the measured pannus area and the mean transaortic pressure gradient of the prosthetic aortic valve.
Conclusion
2
RT-3DTEE can improve the sensitivity and specificity of ultrasonic diagnosis of pannus in the prosthetic aortic valve and allows accurate evaluation of the degree of valve obstruction caused by the pannus
thus providing reliable evidence to facilitate the diagnosis and treatment of the condition.
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