400038 重庆,陆军军医大学(第三军医大学)第一附属医院关节外科
Received:18 August 2019,
Revised:2019-09-04,
Published:15 October 2019
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Liu YANG, Fuyou WANG. Progress of 3D printed porous tantalum in orthopedics[J]. Journal of Third Military Medical University, 2019, 41(19): 1859-1866.
Liu YANG, Fuyou WANG. Progress of 3D printed porous tantalum in orthopedics[J]. Journal of Third Military Medical University, 2019, 41(19): 1859-1866. DOI: 10.16016/j.1000-5404.201908136.
钽具有“亲生物”金属之称,具有极佳的生物惰性和生物相容性。纯钽应用于骨科医疗至今已经80多年。由于纯钽与骨组织弹性模量相差较大,不利于骨结合,然而多孔钽却在提供力学强度的同时可减少应力遮挡,有利于应力传导,便于骨骼塑形,同时具有优良的骨诱导性,广泛应用于骨科领域,并取得了理想疗效。但是由于人体的差异性、骨缺损部位形态的随机性,如骨肿瘤患者、骨畸形患者等,标准化多孔钽已经不能满足患者个性化治疗要求。从临床医学发展趋势看,最好的治疗方法应该是个性化治疗,最好的植入体应该是个性化植入体。未来需要解决钽粉原材料及价格、专用设备及工艺、3D打印工艺与传统工艺的差异、多组分梯度打印等方面的问题。
Tantalum
known as "pro-biometal"
has excellent bio-inertness and bio-compatibility. Pure tantalum has been used in orthopedics for longer than 80 years. But pure tantalum has little in common with bone tissue in the elastic modulus and is not conducive to osseointegration
while
porous tantalum can not only provide mechanical strength but also reduce stress occlusion
facilitate stress conduction
promote bone shaping
and has excellent osteoinduction
which is widely used in orthopedics and has achieved ideal outcomes. However
due to great diversities in human body and randomness of bone defect sites
such as patients with bone tumors and those with bone deformities
standardized porous tantalum is unable to meet the patients' individualized treatment requirements. From the perspective of clinical development
the optional treatment should be individualized
and the best implant should also be individualized. In the future
we need to focus on the following problems
tantalum powder and its price
special equipment and manufacturing process
differences between 3D and traditional manufacure
and multicomponent gradients and others.
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